Osteoarthritis of the Knee Clinical Trials

206 clinical trials for Osteoarthritis of the Knee across international registries, including 21 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Phase III Study of CLS2901C in Patients With Osteoarthritis of the Knee — RECRUITING · PHASE3
• Efficacy of Aerobic Exercise Versus Therapeutic Exercises on Exercise-induced Hypoalgesia in Knee Osteoarthritis — RECRUITING · NA
• Establishment of an online programme for physiotherapy in patients with gonarthrosis and coxarthrosis — RECRUITING
• Study to Assess the Safety and Pharmacokinetics of AVD275 Injection in Patients With Osteoarthritis of the Knee — RECRUITING · PHASE1
• MASTER PROTOCOL: A MASTER PROTOCOL FOR PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDIES TO INVESTIGATE THE EFFICACY AND SAFETY OF ONCE WEEKLY ELORALINTIDE IN ADULT PARTICIPANTS WITH OSTEOARTHRITIS KNEE PAIN, AND OBESITY OR OVERWEIGHT (ENLIGHTEN-4) — RECRUITING · PHASE3
• EFFICACY AND SAFETY OF NNC0487-0111 S.C. ONCE-WEEKLY IN PARTICIPANTS WITH OVERWEIGHT OR OBESITY, AND KNEE OSTEOARTHRITIS (AMAZE 6) — RECRUITING
• EFFICACY AND SAFETY OF NNC0487-0111 S.C. ONCE-WEEKLY IN PARTICIPANTS WITH OVERWEIGHT OR OBESITY, AND KNEE OSTEOARTHRITIS (AMAZE 5) — RECRUITING
• A PHASE 3 STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF ORFORGLIPRON ONCE DAILY IN PARTICIPANTS WHO HAVE OBESITY OR OVERWEIGHT AND OSTEOARTHRITIS OF THE KNEE: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PARALLEL-ARM, PLACEBO-CONTROLLED TRIAL (ATTAIN-OA PAIN) — RECRUITING · PHASE3
• Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee — RECRUITING · PHASE2
• SINGLE DOSE PARALLEL COMPARATIVE BIOAVAILABILITY STUDY OF TRIAMCINOLONE HEXACETONIDE FOLLOWING INTRA-ARTICULAR ADMINISTRATION OF A SINGLE DOSE INJECTION OF TRIAMCINOLONE HEXACETONIDE (20 MG/ML) OR OF THE COMBINATION OF TRIAMCINOLONE HEXACETONIDE (18 MG/4 ML) AND CROSS-LINKED HYALURONIC ACID VISCOSUPPLEMENT IN MALE AND FEMALE PATIENTS WITH OSTEOARTHRITIS OF THE KNEE — RECRUITING
• Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection — RECRUITING · NA
• RECOMBINANT HUMAN GROWTH HORMONE (RHGH) FOR KNEE OSTEOARTHRITIS (KORR): A PILOT, RANDOMIZED PLACEBO-CONTROLLED TRIAL — RECRUITING
• RObotic-assisted Versus Conventional Knee Endoprosthetic Techniques — RECRUITING · NA
• A MULTICENTER RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-FINDING, PHASE 2 STUDY (MARS-17) OF GSK3858279 IN ADULT PARTICIPANTS WITH MODERATE TO SEVERE PAIN DUE TO KNEE OSTEOARTHRITIS — RECRUITING · PHASE2
• A 2-STAGE, ADAPTIVE, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTRE STUDY TO EVALUATE DOSE AND TREATMENT EFFECT OF PENTOSAN POLYSULFATE SODIUM COMPARED WITH PLACEBO IN PARTICIPANTS WITH KNEE OSTEOARTHRITIS PAIN — RECRUITING
• INTRA-ARTICULAR AUTOLOGOUS BONE MARROW ASPIRATE CONCENTRATE VS PLACEBO AND LIPOASPIRATE CONCENTRATE WITH LEUKOCYTE-POOR PLATELET RICH PLASMA VS PLACEBO INJECTION EVALUATIONS FOR TREATMENT OF KNEE OSTEOARTHRITIS: THE ABLE OA DOUBLEBLINDED RANDOMIZED CLINICAL TRIAL INJECTION — RECRUITING
• A MULT. ARM, MULTICENTER, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-ARM, PHASE 2 STUDY OF INTRA-ARTICULAR ADMINISTRATION OF AN ALLOGENEIC HUMAN PLACENTAL TISSUE PARTICULATE (PTP-001) FOR THE TREATMENT OF KNEE OSTEOARTHRITIS — RECRUITING · PHASE2
• A 5-YEAR, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER STUDY ASSESSING THE EFFICACY, SAFETY, AND TOLERABILITY OF INTRA-ARTICULAR REGIMENS OF LNA043 VERSUS PLACEBO IN PATIENTS WITH SYMPTOMATIC KNEE OSTEOARTHRITIS (ONWARDS) — RECRUITING
• EFFECT OF SUBCUTANEOUS SEMAGLUTIDE 2.4 MG ONCE-WEEKLY COMPARED TO PLACEBO IN SUBJECTS WITH OBESITY AND KNEE OSTEOARTHRITIS — RECRUITING
• A DOUBLE-BLIND, PLACEBO-CONTROLLED, 4-ARM, PHASE 2B STUDY TO ASSESS THE EFFICACY AND SAFETY OF A 14-DAY DOSING REGIMEN OF 3 DOSES OF ATB-346 VERSUS PLACEBO, ORALLY ADMINISTERED ONCE DAILY TO MALE AND FEMALE PATIENTS DIAGNOSED WITH OSTEOARTHRITIS OF THE KNEE — RECRUITING · PHASE2
• "A PHASE 1, OPEN-LABEL, NON-RANDOMIZED STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF [TC-99M]-RPI-T-087 INJECTION AS AN IMAGING MARKER FOR COX-2 IN SUBJECTS WITH OSTEOARTHRITIS OF THE KNEE COMPARED TO HEALTHY VOLUNTEERS." — RECRUITING · PHASE1
• A randomized clinical trial to investigate the efficacy and safety of the combination of intra-articular hyaluronan and corticosteroids for osteoarthritis of the knee Ensayo clínico aleatorizado para evaluar la eficacia y seguridad de la combinación del ácido hialurónico y corticoides intraarticulares en la artrosis de rodilla — ACTIVE_NOT_RECRUITING · PHASE4
• 'Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) as an outcome measure to evaluate the effectiveness of intra-articular hyaluronic acid for knee osteoarthritis’ — ACTIVE_NOT_RECRUITING · PHASE4
• A Double-Blind, Double-Dummy, Randomized, Active-Comparator, Arthritis Non-Inferiority Study of LT-NS001 versus Naprosyn® for Twelve Weeks in Osteoarthritis Patients to Compare Endoscopic Gastric Ulcer Rates — COMPLETED · PHASE2
• An open label study of intra-articular steroid injection in the management of symptomatic knee OA — COMPLETED · PHASE4
• A Phase 2, Randomized, Double-blind, Placebo-controlled Crossover Study Evaluating the Efficacy and Safety of LTG-321 in Patients with Osteoarthritis of the Knee — TERMINATED · PHASE2
• 3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee Osteoarthritis — TERMINATED · PHASE3
• Pilot Study to Identify and Validate Digital Biomarkers in Osteoarthritis of the Knee — COMPLETED · NA
• A Pilot, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Tolerability, Safety, and Pharmacokinetics of a Single Intra-articular Injection of CNTX-0066 in Participants with Chronic, Moderate-to-Severe Osteoarthritis Knee Pain — NOT_YET_RECRUITING · PHASE1
• A Phase 2, Randomized, Double-blind, Placebo-controlled Crossover Study Evaluating the Efficacy and Safety of LTG-001 in Patients with Osteoarthritis of the Knee — NOT_YET_RECRUITING · PHASE2
• Efficacy and Safety Study of PG201 Tablet in Patients With Osteoarthritis — WITHDRAWN · PHASE2
• Intra-Articular Polyacrylamide Hydrogel Injections Improve Pain and Function in Knee Osteoarthritis — COMPLETED
• PRELIMINARY DOSIMETRY STUDY OF HOMOGENEOUS 117MSN HYDROXIDE MICRIPARTICLES FOR RADIOSYNOVIORTHESIS IN PATEINTS WITH OLSTEOARTHRITIS OF THE KNEE — NOT_YET_RECRUITING
• Analgesic Effects of a Treatment With Cannabis Sativa Extract in Patients With Knee Osteoarthritis - CANOA (Cannabis for Osteoarthritis) — COMPLETED · PHASE2
• Postmarketing Multicenter Study of Intra-Articular DIART ONE / EASYGO ONE for Knee Osteoarthritis — COMPLETED
• A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee Marching On for Veterans With Osteoarthritis of the Knee — ACTIVE_NOT_RECRUITING · PHASE3
• ATTUNE Cementless FB Tibial Base Clinical Study — TERMINATED · NA
• Multicentre GMK UNI Anatomical Cementless Study - FR — ACTIVE_NOT_RECRUITING
• Functional and Clinical Outcomes of Hyaluronic Acid and Steroid Injections in Bilateral Knee Osteoarthritis — COMPLETED · PHASE4
• A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee — COMPLETED · PHASE2
• A Phase 2, Open Label, Pharmacokinetic (PK) Study of TLC599 in Subjects With Osteoarthritis of the Knee — COMPLETED · PHASE2
• Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis — WITHDRAWN · PHASE1
• Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain — COMPLETED · PHASE3
• Shengyu Decoction and Lijin Manipulation for Knee OA: 3D Gait Analysis — OTHER · PHASE1
• Phase IIa, Randomized, Double Blinded, Placebo Controlled, Dose Finding Study for TLC599 in OA Patients — COMPLETED · PHASE2
• Study to Characterize the PK and Local Extent and Duration of Exposure From FX006 in Patients With OA of the Knee — COMPLETED · PHASE2
• A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cryo-Touch III Device — COMPLETED · NA
• Study to Characterize the Local Duration of Exposure From FX006 in Patients With Osteoarthritis of the Knee — COMPLETED · PHASE2
• Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee — COMPLETED · PHASE2
• Study of FX006 in Patients With Osteoarthritis of the Knee — COMPLETED · PHASE2

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