Osteogenesis Imperfecta Clinical Trials

98 clinical trials for Osteogenesis Imperfecta across international registries, including 19 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Losartan for older adolescents and adults with osteogenesis imperfecta — RECRUITING · PHASE2
• Multicenter, Safety Follow-up Study to Assess Safety of Prior Treatment with Romosozumab in Children and Adolescents with Osteogenesis Imperfecta — RECRUITING · PHASE3
• Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN) — RECRUITING · PHASE2
• A Dose REgimen-Finding Study of AGA2115 in Chinese Patients With Osteogenesis ImpeRfecta (EIR) — RECRUITING · PHASE2
• Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta — RECRUITING · PHASE3
• Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Osteogenesis Imperfecta — RECRUITING · NA
• Effects of Bisphosphonates on OI-Related Hearing Loss — RECRUITING · PHASE4
• REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD) — RECRUITING · NA
• Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta — RECRUITING
• Registry of Osteogenesis Imperfecta — RECRUITING
• A PHASE 2, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSERANGING STUDY TO EVALUATE THE SAFETY AND EFFICACY OF AGA2115 IN ADULTS WITH TYPE I, III, OR IV OSTEOGENESIS IMPERFECTA (OI) — RECRUITING · PHASE2
• Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta — RECRUITING
• BBD Longitudinal Study of Osteogenesis Imperfecta — RECRUITING
• A PHASE 3, OPEN-LABEL, MULTICENTER, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ROMOSOZUMAB COMPARED WITH BISPHOSPHONATES IN CHILDREN AND ADOLESCENTS WITH OSTEOGENESIS IMPERFECTA — RECRUITING · PHASE3
• AN OPEN-LABEL, RANDOMIZED, ACTIVE-CONTROLLED, PHASE 3 STUDY OF SETRUSUMAB COMPARED WITH BISPHOSPHONATES IN PEDIATRIC SUBJECTS WITH OSTEOGENESIS IMPERFECTA TYPES I, III OR IV — RECRUITING · PHASE3
• A PHASE 1B, SINGLE ASCENDING DOSE, RANDOMIZED, DOUBLE-BLIND STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND ACTIVITY OF SAR439459 IN ADULTS WITH OSTEOGENESIS IMPERFECTA — RECRUITING · PHASE1
• A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 2/3 STUDY TO ASSESS THE EFFICACY AND SAFETY OF SETRUSUMAB IN SUBJECTS WITH OSTEOGENESIS IMPERFECTA (OI) — RECRUITING · PHASE2
• "MULTICENTER, SINGLE-ARM OPEN-LABEL EXTENSION STUDY TO ASSESS LONG-TERM SAFETY AND EFFICACY OF CURRENT OR PRIOR TREATMENT WITH DENOSUMAB IN CHILDREN/YOUNG ADULTS WITH OSTEOGENESIS IMPERFECTA — RECRUITING
• A PHASE 2B, MULTICENTRE, MULTINATIONAL, PLACEBO-CONTROLLED, DOUBLE-BLIND, DOSE-FINDING STUDY IN ADULT PATIENTS WITH TYPE I, III OR IV OSTEOGENESIS IMPERFECTA TREATED WITH BPS804 — RECRUITING · PHASE2
• Treatment of osteogenesis imperfecta with parathyroid hormone and zoledronic acid — ACTIVE_NOT_RECRUITING
• Brittle bones - do they react normally after treatment with bisphosphonates? — COMPLETED · PHASE2
• An international, multicenter, randomized, open-label, safety and efficacy trial of intravenous zoledronic acid administered either once or twice yearly in children with severe osteogenesis imperfecta, a 1-year extension to CZOL446H2202 — TERMINATED · PHASE2
• Study on the effect of r-hGH in combination with bisphosphonate treatment on bone metabolism in Osteogenesis Imperfecta — COMPLETED · PHASE4
• A Phase 2, Multi-center, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Safety and Efficacy of AGA2115 in Adults with Type I, III, or IV Osteogenesis Imperfecta (OI) — NOT_YET_RECRUITING · PHASE2
• Evaluation and Treatment of Patients With Connective Tissue Disease — COMPLETED
• Matrix-Directed Therapy In Older Adolescents And Adults With Osteogenesis Imperfecta – The “MOI-A” Study — TERMINATED · PHASE2
• Evaluation and Intervention for the Effects of Osteogenesis Imperfecta — COMPLETED
• Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis — NOT_YET_RECRUITING · NA
• Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta — ACTIVE_NOT_RECRUITING · PHASE3
• Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid — COMPLETED · PHASE4
• An Operationally Seamless, Randomized Phase 2/3 Study Consisting of a Phase 2 Single Blind, Dose-Evaluation Phase and a Phase 3 Double-Blind, Placebo-controlled Phase to Assess the Efficacy and Safety of Setrusumab in Subjects with Osteogenesis Imperfecta — TERMINATED · PHASE3
• Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta — ACTIVE_NOT_RECRUITING · PHASE3
• Increasing Knowledge on Osteogenesis Imperfecta by Collecting Epidemiological Data — COMPLETED · NA
• Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI) — NOT_YET_RECRUITING · PHASE1
• Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708 — ACTIVE_NOT_RECRUITING
• Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta — ACTIVE_NOT_RECRUITING · PHASE3
• Setrusumab vs Placebo for Osteogenesis Imperfecta — ACTIVE_NOT_RECRUITING · PHASE2
• Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and Genotype Phenotype Correlation — COMPLETED
• Dental Malocclusion and Craniofacial Development in OI — ACTIVE_NOT_RECRUITING
• Post-market Observational Study on JTIN Telescopic Nail in Osteogenesis Imperfecta Pediatric Patients — COMPLETED
• Clear Aligners for the Treatment of Dental Malocclusion in OI — ACTIVE_NOT_RECRUITING · NA
• Urinary Biomarkers of OI Pathobiology — ACTIVE_NOT_RECRUITING
• Pediatric Arthropathy Beyond Inflammation: Clinical Spectrum and Diagnostic Approach at Assiut University Children Hospital — NOT_YET_RECRUITING
• Boost Brittle Bones Before Birth — ACTIVE_NOT_RECRUITING · PHASE1
• Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI) — TERMINATED · PHASE1
• Evaluation of the Benefits of Adaptive Physical Activity in Children and Adolescents With Osteogenesis Imperfecta — COMPLETED · NA
• Epigenetic Regulation of Osteogenesis Imperfecta Severity : miROI Study — COMPLETED · NA
• Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta — TERMINATED · PHASE2
• Osteogenesis Imperfecta Blood Pressure Study — COMPLETED
• Pain characterization and cluster analysis in patients with connective tissue disease and fibromyalgia syndrome — OTHER

Refine this search