Primary Biliary Cirrhosis Clinical Trials

89 clinical trials for Primary Biliary Cirrhosis across international registries, including 11 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Safety and efficacy of elafibranor therapy in patients with primary biliary cholangitis and liver cirrhosis. — RECRUITING
• Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome — RECRUITING
• Biobank for Cholestatic Liver Diseases. — RECRUITING
• Treatment uptake of second line therapies in patients with primary biliary cholangitis and missing deep response on ursodeoxycholic acid — RECRUITING
• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford — RECRUITING
• sCD163 in PBC Patients - Assessment of Treatment Response — RECRUITING
• Bezafibrate in Patients With Primary Biliary Cholangitis (PBC) — RECRUITING
• SEAL - Structured Early Assessment of Asymptomatic Liver Fibrosis and Cirrhosis — RECRUITING
• A Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Assess the Efficacy and Safety of Oral GKT137831 in Patients with Primary Biliary Cholangitis Receiving Ursodeoxycholic Acid and with Persistently Elevated Alkaline Phosphatase — RECRUITING
• A MULTI-PART, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO ASSESS THE SAFETY, TOLERABILITY AND EFFICACY OF LJN452 IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS — RECRUITING
• A 12-WEEK, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PHASE 2 STUDY, TO EVALUATE THE EFFECTS OF TWO DOSES OF MBX-8025 IN SUBJECTS WITH PRIMARY BILIARY CIRRHOSIS (PBC) AND AN INADEQUATE RESPONSE TO URSODEOXYCHOLIC ACID (UDCA) — RECRUITING · PHASE2
• The effect of Ezetimibe or pyridoxine in Patients with Primary Biliary Cirrhosis. — TERMINATED · PHASE4
• TruGraf Liver Gene Expression Serial Test — TERMINATED
• Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) — ACTIVE_NOT_RECRUITING · PHASE3
• Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC) — ACTIVE_NOT_RECRUITING · PHASE3
• Prospective, multicentric observational study on the application of ASEPT® and on results from patient surveys in palliative care — OTHER
• Structured nutritional intervention for chronic fatigue in patients with primary biliary cholangitis: a cross-sectional and single-blinded randomized controlled clinical trial — NOT_YET_RECRUITING
• Real Life Analysis of new PPAR agonists for treatment of PBC — NOT_YET_RECRUITING
• Repeatability and Reproducibility of Multiparametric MRI — COMPLETED
• Genetic Epidemiology of Primary Biliary Cirrhosis (PBC) — COMPLETED
• The Health Burden of Primary Biliary Cirrhosis (PBC) in Switzerland — COMPLETED
• Study to Evaluate the Effects of Two Doses of Seladelpar (MBX-8025) in Subjects With Primary Biliary Cirrhosis (PBC) — TERMINATED · PHASE2
• Highly Active Antiretroviral Therapy for Patients With Primary Biliary Cirrhosis — TERMINATED · NA
• Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis — COMPLETED · PHASE2
• Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation for Children Suffering From Biliary Atresia — COMPLETED · PHASE1
• Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis — COMPLETED · PHASE2
• A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384 — COMPLETED · PHASE1
• An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects — COMPLETED · PHASE1
• Online Wellness Intervention for Primary Biliary Cholangitis (PBC) — COMPLETED · NA
• Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis — COMPLETED · PHASE3
• Fenofibrate for Patients With Primary Biliary Cirrhosis Who Had An Inadequate Response to Ursodeoxycholic Acid — OTHER · PHASE3
• Phase 2 Study on Effects of Obeticholic Acid (OCA) on Lipoprotein Metabolism in Participants With Primary Biliary Cirrhosis — COMPLETED · PHASE2
• sCD163 in PBC Patients - Assessment of Disease Severity and Prognosis — ACTIVE_NOT_RECRUITING
• Mind-body Wellness Intervention in Primary Biliary Cholangitis (PBC) — COMPLETED · NA
• Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC) — COMPLETED · PHASE2
• Study to Assess Safety & Efficacy of GKT137831 in Patients With Primary Biliary Cholangitis Receiving Ursodiol. — COMPLETED · PHASE2
• Efficacy and Safety of Fenofibrate Combined With UDCA in PBC Patients With an Incomplete Biochemical Response to UDCA — WITHDRAWN · PHASE1
• Study of Obeticholic Acid（OCA） Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC) — OTHER · PHASE3
• A Randomised Clinical Trial Assessing the Efficacy and Safety of Mycophenolate Mofetil Versus Azathioprine for Induction of Remission in Treatment Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome — OTHER · PHASE4
• PBC Induced Fatigue Treated With Thiamine — OTHER · PHASE4
• Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis — COMPLETED · PHASE3
• A Study to Assess Efficacy and Safety of Bezafibrate in Patients With Primary Biliary Cholangitis — OTHER · PHASE3
• Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis — COMPLETED · NA
• Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity — COMPLETED
• Study of Abatacept (Orencia) to Treat Primary Biliary Cirrhosis — COMPLETED · PHASE4
• A Study of TQA3526 in the Treatment of Primary Biliary Cirrhosis (PBC) — OTHER · PHASE2
• Ursodeoxycholic Acid Plus Budesonide Versus Ursodeoxycholic Acid Alone in Primary Biliary Cirrhosis (PBC) — TERMINATED · PHASE3
• Gut Microbes and Metabolic Group in Different PBC Patients for UDCA Response — COMPLETED
• Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT — COMPLETED · PHASE1
• Repeatability and Reproducibility of Quantitative MRCP — COMPLETED

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