Rectal Cancer Clinical Trials

998 clinical trials for Rectal Cancer across international registries, including 176 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients — RECRUITING · PHASE1
• Contact Radiotherapy for Rectal Cancer — RECRUITING · NA
• Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT) — RECRUITING · NA
• SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer — RECRUITING · PHASE2
• Distance-Based Exercise to Preserve Function and Prevent Disability — RECRUITING · NA
• Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H) — RECRUITING · NA
• A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer. — RECRUITING · PHASE2
• Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome — RECRUITING · NA
• Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer — RECRUITING · NA
• Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement — RECRUITING · PHASE2
• Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer — RECRUITING · PHASE3
• Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) — RECRUITING · NA
• Efficacy and Safety of the CG-100 Intraluminal Bypass Device — RECRUITING · NA
• Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer — RECRUITING · PHASE2
• Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery — RECRUITING · PHASE2
• Integrated Cancer Repository for Cancer Research — RECRUITING
• Active Surveillance vs Adjuvant Chemoradiotherapy for Locally Resected Intermediate-Risk T1 Rectal Cancer — RECRUITING · NA
• Interest of PET-MRI in the Evaluation of the Response After Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma — RECRUITING
• SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak — RECRUITING · PHASE4
• The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer — RECRUITING · NA
• Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC — RECRUITING · PHASE2
• A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression — RECRUITING · PHASE1
• A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL) — RECRUITING · PHASE2
• Mesorectal Microbiome and Metabolome as a Prognostic Factor in Patients With Rectal Cancer — RECRUITING
• ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer — RECRUITING · PHASE3
• FOLFIRINOX Induction Chemotherapy for Synchronous Liver Metastases — RECRUITING
• Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique) — RECRUITING · NA
• A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer — RECRUITING · NA
• Higher Radiation Dose to the Tumor May Help Avoid Surgery in Rectal Cancer Patients — RECRUITING · NA
• Adjuvant chemotherapy for prevention of recurrence in patients with detectable ctDNA after surgery in high-riskrectal cancer. — RECRUITING · PHASE3
• Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection — RECRUITING · NA
• EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer. — RECRUITING · NA
• Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial — RECRUITING · PHASE2
• A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer — RECRUITING · PHASE3
• Brodalumab in the Treatment of Immune-Related Adverse Events — RECRUITING · PHASE1
• A Study of Tucatinib and Trastuzumab in People With Rectal Cancer — RECRUITING · PHASE2
• Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer — RECRUITING · PHASE3
• The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer — RECRUITING · NA
• Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. — RECRUITING · PHASE2
• Exosomes in Rectal Cancer — RECRUITING
• Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance — RECRUITING · PHASE3
• Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors — RECRUITING · PHASE1
• Rectal Cancer Neoadjuvant Therapy-Real World Study — RECRUITING
• Longterm Functional Outcomes in Patients Undergoing Organ Preserving Treatment for Rectal Cancer With or Without Local Excision After Chemoradiotherapy — RECRUITING
• Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy — RECRUITING · PHASE1
• Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer — RECRUITING · PHASE3
• Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial — RECRUITING · PHASE3
• Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer — RECRUITING · NA
• A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer — RECRUITING · PHASE2
• Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI — RECRUITING

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