Recurrent depressive disorder, current episode severe without psychotic symptoms Clinical Trials

72 clinical trials for Recurrent depressive disorder, current episode severe without psychotic symptoms across international registries, including 23 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• The impact of transcranial direct current stimulation (tDCS) on open-label placebo effects — RECRUITING
• Investigating the efficacy of add-on acceptance and commitment therapy in the inpatient setting for depression and sleep disorders - a randomized controlled trial — RECRUITING
• Acute effects of transcranial direct currrent stimulation (tDCS) on neuropsychological and affective outcomes in older adults and with depressive disorder. — RECRUITING
• SleepLess - Imaging synaptic plasticity in therapeutic sleep deprivation for major depression — RECRUITING
• Network and control theory for difficult-to-treat mood and anxiety disorders (NECTAR) — RECRUITING
• Efficacy and Safety of a Brief Transdiagnostic Cognitive Behavioral Intervention: A Randomized Controlled Trial — RECRUITING
• A Randomized Clinical Trial Comparing Active Versus Sham T-PEMF Headband Treatment for Depression — RECRUITING · NA
• A pilot study on the effects of tactile emotion transmission in video-based psychotherapy for unipolar depression — RECRUITING
• Smartphone-Based Phenotyping of Suicidality and Interpersonal Risk Factors – An Ecological Momentary Assessment Study — RECRUITING
• Perfectionism-related variation in error processing of depressive patients – an EEG study before and after psychotherapy — RECRUITING
• Investigation of the efficacy of a short-intervention implementing chairwork in patients with depressive disorders - a randomized controlled trial. — RECRUITING
• Intervention for the Treatment of Depression in Virtual Reality (FlowVR) — RECRUITING
• Evaluation of an app for self-directed processing of therapeutic content for patients with unipolar depression — RECRUITING
• Investigating the efficacy of an add-on acceptance and commitment inpatient therapy in gerontopsychiatric patients diagnosed with depression and chronic pain - a randomized controlled trial. — RECRUITING
• Augmenting treatment for Major Depression with a Positivity-AAT-Training — RECRUITING
• Blood brain barrier permeability and inflammatory biomarkers in patients with depression — RECRUITING
• „Better with dad" Process and outcome of inpatient-mother-child therapies for postpartum mental disorders: Prozess und Outcome stationärer Mutter-Kind: Contributing factors and predictors in the field of maternal and paternal relationships. — RECRUITING
• Clinical and Cost-Effectiveness of PSYCHOnlineTHERAPY: a multicenter blended outpatient psychotherapy cluster randomized controlled trial for patients with depressive and anxiety disorders — RECRUITING
• Health service research for integrative mental health care compared to treatment as usual in an in-patient setting. — RECRUITING
• Investigating Care Dependency And its Relation to OutcomE (ICARE) — RECRUITING
• A randomized, double-blind controlled study of the efficacy of infrared-whole body hyperthermia in patients with major depression — RECRUITING
• REM-sleep disruption and changes in noradrenergic neuronal reaction patterns in patients with sleep disorders or major depression — RECRUITING
• Physical activity as a dysfunctional emotion regulation strategy in youth patients with anorexia nervosa - a comparison study across different disorders using ecological momentary assessment — RECRUITING
• Video-based outpatient psychotherapy in psychotherapeutic care - Group therapy — OTHER
• Optimization of Post-Hospital Care for People with Severe Mental Illness through Empowerment, Participation, and Digitalization — NOT_YET_RECRUITING
• The Effect of Stress on Neuroendocrine Markers and Functional Connectivity in Children and Adolescents with Depressive and Anxiety Disorders — OTHER
• Walk and Talk Psychotherapy in Nature – A Pilot Study to Assess Feasibility — OTHER
• Controlled Randomized Clinical Trial to assess Efficacy of Deep Brain Stimulation (DBS) of the slMFB in Patients with Treatment Resistant Major Depression — OTHER
• Virtual reality in the treatment of unipolar depressive disorders — OTHER
• Using a multi-omics approach to predict treatment outcome in MDD patients (PredictOMICS) — NOT_YET_RECRUITING
• Vascular Effects of Electroconvulsive Therapy: A Neurosonographic Study — OTHER
• Increasing approach tendencies for positive socio-emotional cues in depression — OTHER
• Augmentation of Interpersonal Psychotherapy (IPT) with D-cycloserine — OTHER
• The effect of interventions focussing on or leading away from actual symptoms on well-being in different states of altered neuroplasticity — OTHER
• Systematic investigation of somatic care among patients with a severe mental illness at the LVR-Hospital Düsseldorf — OTHER
• Mindfulness-based receptive music therapy for people with depression – A controlled pilot study to evaluate heart rate variability and mindfulness — OTHER
• Improving the quality of treatment for severely mentally ill people to reduce somatic comorbidity and prevent increased mortality — OTHER
• Quantitative EEG- and EMG-analysis during electroconvulsive therapy — OTHER
• Laboratory parameters before and after epileptic seizures — OTHER
• Mental disorders in the workplace and return to work: a mixed-methods-follow-up study on determinants of a successful return to work among employees with common mental disorders. — OTHER
• Efficacy and Cost Effectiveness of the Implementation of a Supervised, Transdiagnostic Group-based Exercise Intervention Named ImPuls for Patients With Major Depression, Panic Disorder, Agoraphobia, Post-traumatic Stress Disorder and Nonorganic Insomnia Within a Naturalistic Outpatient Setting in Germany: a Pragmatic RCT — OTHER
• Effects of digital cognitive-behavioral psychotherapy for insomnia (dCBT-I) KVT-I on depression — OTHER
• Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression (EPIsoDE) — OTHER
• Evaluation of striatal dopamine transporter availability in patients with therapyresistent major depression, treated by sleep deprivation and electroconvulsive therapy — OTHER
• Diagnostic value of [18F]FDG PET for differential diagnosis of pseudo-dementia — OTHER
• Simvastatin add-on to Escitalopram in Patients With Comorbid Obesity and Major Depression: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial — OTHER
• Functional and structural neuronal changes after a video game training intervention in adult patients with depression — OTHER
• A modular add-on approach for patients with comorbid depression and a history of childhood maltreatment — OTHER
• Depression in adolescents: A double-blind randomised controlled trial of Bright Light Therapy in a naturalistic inpatient setting. — OTHER
• How do adverse childhood experiences and psychiatric disorders impact social cognition? — OTHER

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