Recurrent Glioblastoma Clinical Trials

176 clinical trials for Recurrent Glioblastoma across international registries, including 42 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma — RECRUITING · PHASE1
• Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells — RECRUITING · PHASE1
• Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM — RECRUITING · PHASE3
• A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial — RECRUITING · NA
• A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM — RECRUITING · PHASE1
• A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial — RECRUITING · PHASE2
• Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma — RECRUITING · PHASE1
• Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma — RECRUITING · NA
• Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma — RECRUITING · NA
• MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma — RECRUITING · PHASE1
• CARv3-TEAM-E T Cells in Glioblastoma — RECRUITING · PHASE1
• Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma — RECRUITING · PHASE1
• Sitagliptin in Recurrent/Progressive Grade 4 Glioma — RECRUITING · PHASE1
• Dosimetry, Safety, and Efficacy Study of [177Lu]Lu-XT771 in Patients With Recurrent Glioblastoma — RECRUITING · PHASE1
• Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma — RECRUITING · PHASE1
• RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM) — RECRUITING · PHASE1
• A study to investigate how a single dose of the drug melflufen reaches brain tumor tissue, and how it affects the tumour, in patients who are already scheduled for surgery for a returning glioblastoma — RECRUITING · PHASE1
• Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM — RECRUITING · PHASE1
• A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma — RECRUITING · PHASE2
• Sonodynamic Therapy in Patients With Recurrent GBM — RECRUITING · PHASE1
• Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma — RECRUITING · PHASE1
• Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent Glioblastoma — RECRUITING · PHASE1
• Sacituzumab Govitecan in Recurrent Glioblastoma — RECRUITING · PHASE2
• Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma — RECRUITING · PHASE1
• CUE-102 in Recurrent Glioblastoma — RECRUITING · PHASE1
• Surgical Pembro +/- Olaparib w TMZ for rGBM — RECRUITING · PHASE2
• Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer — RECRUITING · PHASE2
• Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma — RECRUITING · PHASE1
• OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial — RECRUITING · PHASE2
• Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma — RECRUITING · PHASE1
• B7H3/IL13Ra2 Bispecific Armored Chimeric Antigen Receptor T-Cell Therapy Study for Recurrent/Refractory Glioblastoma — RECRUITING · PHASE1
• Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma — RECRUITING · NA
• A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma — RECRUITING · PHASE1
• A Study of BL-B01D1 in Patients With Recurrent Glioblastoma — RECRUITING · PHASE2
• Pilot Trial for Treatment of Recurrent Glioblastoma — RECRUITING · PHASE1
• Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma — RECRUITING · PHASE1
• A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent Glioblastoma — RECRUITING · PHASE1
• Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma — RECRUITING · PHASE2
• Tris-CAR-T Cell Therapy for Recurrent Glioblastoma — RECRUITING · PHASE1
• The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) — RECRUITING
• The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma — RECRUITING
• The Efficacy and Safety of Low-dose Radiotherapy Combined With Sintilimab and Temozolomide in Recurrent Glioblastoma — RECRUITING · PHASE2
• Phase II study Systemic treatment with ZK219477 EPOTHILONE in recurrent Glioblastoma patients — COMPLETED · PHASE2
• BRIOChe: A trial looking at re-irradiation and chemotherapy in patients with recurrent glioblastoma. — OTHER · PHASE2
• Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields — ACTIVE_NOT_RECRUITING · PHASE2
• Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma — ACTIVE_NOT_RECRUITING · PHASE2
• Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma — SUSPENDED · PHASE2
• OLIG2 Inhibitor CT-179 for Recurrent and Newly-diagnosed Glioblastoma — NOT_YET_RECRUITING · PHASE1
• Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma — ACTIVE_NOT_RECRUITING · PHASE1
• DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma — ACTIVE_NOT_RECRUITING · NA

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