Secondary Progressive Multiple Sclerosis Clinical Trials

72 clinical trials for Secondary Progressive Multiple Sclerosis across international registries, including 7 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis — RECRUITING · PHASE3
• A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis — RECRUITING · PHASE3
• Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis — RECRUITING · PHASE1
• The Effect of Rituximab on Cognitive and Hand Functions in Secondary Progressive Multiple Sclerosis — RECRUITING · PHASE2
• Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) — RECRUITING · PHASE3
• SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis — RECRUITING · PHASE1
• Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis — RECRUITING
• A Clinical Study of the Efficacy of Natalizumab on Reducing Disability Progression in Subjects With SPMS — TERMINATED · PHASE3
• An extension trial of intrathecal therapy with monoclonal antibodies in progressive multiple sclerosis — COMPLETED · PHASE2
• Novel Imaging Markers in SPMS — COMPLETED · PHASE1
• A randomized, double-blind, placebo-controlled Phase III study to evaluate the efficacy and safety of remibrutinib in patients with secondary progressive multiple sclerosis — TERMINATED · PHASE3
• A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients — ACTIVE_NOT_RECRUITING · PHASE2
• Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis — ACTIVE_NOT_RECRUITING · PHASE3
• Functional Outcomes From Diets in Multiple Sclerosis — ACTIVE_NOT_RECRUITING · NA
• A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis. — ACTIVE_NOT_RECRUITING · PHASE3
• A Real-world Study About the Impact of Siponimod Treatment on Secondary Progressive Multiple Sclerosis Patients in Russia — COMPLETED
• Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme — COMPLETED · NA
• Metformin Treatment in Progressive Multiple Sclerosis — COMPLETED · PHASE1
• Simvastatin in Secondary Progressive Multiple Sclerosis — COMPLETED · PHASE2
• Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration — ACTIVE_NOT_RECRUITING · PHASE2
• Cladribine Tablets as an Exit Therapy Strategy — NOT_YET_RECRUITING
• Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis — TERMINATED · PHASE2
• Study of NG01 Cell Therapy in Secondary Progressive Multiple Sclerosis — NOT_YET_RECRUITING · PHASE2
• IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis — SUSPENDED · PHASE1
• ACTH in Progressive Forms of MS — TERMINATED · PHASE2
• Transcutaneous Spinal Cord Stimulation (tSCS) in Therapy to Analyze Long-Term Effects on Spasticity and Gait Impairment in Multiple Sclerosis — OTHER
• Multiple Sclerosis-Simvastatin Trial 2 — COMPLETED · PHASE3
• A Real-world Study to Assess the Use of Siponimod in Spain to Treat Patients With Secondary Progressive Multiple Sclerosis — COMPLETED
• Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies — COMPLETED
• Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) — COMPLETED · PHASE4
• Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND) — COMPLETED · PHASE3
• A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis — COMPLETED
• Study to Assess the Safety and Efficacy of an IT Administration of SCM-010 in SPMS — WITHDRAWN · PHASE1
• Evaluate the Safety and Feasibility of Allogeneic Mesenchymal Stem Cells in Patients With Multiple Sclerosis — COMPLETED · PHASE1
• Phase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple Sclerosis — TERMINATED · PHASE1
• Long Term Special Drug Use-results Surveillance for Mayzent in SPMS Patients — COMPLETED
• Improving Cognitive Aptitudes With tDCS in Patients With Multiple Sclerosis — TERMINATED · NA
• Mayzent (Siponimod) Onboarding of Secondary Progressive Multiple Sclerosis (SPMS) Patients With MSGo — COMPLETED
• Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS — WITHDRAWN · PHASE1
• Measuring Active Microglia in Progressive Multiple Sclerosis — COMPLETED
• Safety Study of Human Neural Stem Cells Injections for Secondary Progressive Multiple Sclerosis Patients — COMPLETED · PHASE1
• A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS — COMPLETED · PHASE4
• Patient Research Cohort: Rapidly Evolving Multiple Sclerosis — COMPLETED
• Mechanistic Studies of Phase III Trial With BAF312 in Secondary Progressive Multiple Sclerosis — COMPLETED
• Acceptance Based Telephone Support When Transitioning to SPMS — COMPLETED · NA
• Behavioural Activation for Low Mood in Multiple Sclerosis — COMPLETED · NA
• MS-SMART: Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial — COMPLETED · PHASE2
• Functional Electrical Stimulation for Individuals With Secondary Progressive Multiple Sclerosis — COMPLETED · NA
• Autologous Mesenchymal Stromal Cells for Multiple Sclerosis — COMPLETED · PHASE1
• Investigation of Simvastatin in Secondary Progressive Multiple Sclerosis — COMPLETED · PHASE2

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