Severe Traumatic Brain Injury Clinical Trials

28 clinical trials for Severe Traumatic Brain Injury across international registries, including 6 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Vagus Nerve Stimulation in Patients in Comatose State — RECRUITING · NA
• Feasibility and Safety of Targeting Neutral vs Liberal Fluid Balance in Traumatic Brain Injured Patients- LIMIT-TBI Trial — RECRUITING · PHASE2
• SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury — RECRUITING · NA
• External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial — RECRUITING · NA
• Benchmark Evidence Led by Latin America: Trial of Intracranial Pressure - Pediatrics — RECRUITING · NA
• Incidence, Characteristics and Evolution of Cerebral Vasospasm With Clinical Impact in Moderate to Severe Traumatic Brain Injury Complicated by Subarachnoid Hemorrhage at Martinique University Hospital — RECRUITING · NA
• Copenhagen Head Injury Ciclosporin (CHIC) Study: An open-label, uncontrolled Phase II-study to investigate pharmacokinetics, safety and biomarkers of effectiveness of NeuroSTAT® (ciclosporin) in patients with severe Traumatic Brain Injury (TBI). — TERMINATED · PHASE2
• Valproic AcId for Traumatic BRAin INjury Trial — NOT_YET_RECRUITING · PHASE2
• The Systemic Nature of Severe Traumatic Brain Injury — NOT_YET_RECRUITING
• The Örebro Severe Traumatic Brain Injury Registry — NOT_YET_RECRUITING
• Optimal Cerebral Perfusion Pressure Guided Therapy: Assessment of Target Effectiveness - II — NOT_YET_RECRUITING · NA
• Development and Validation of a Prognostic Model for Neurocritical Patients Using Multimodal Brain Monitoring — NOT_YET_RECRUITING
• Ketamine for Sedation in Severe Traumatic Brain Injury — SUSPENDED · PHASE4
• Cisternostomy Vs Decompressive Craniectomy for Severe Traumatic Brain Injury — OTHER · NA
• Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit. — COMPLETED · NA
• Outcomes Associated With Application of a Normothermia Protocol in Patients With Severe Neurological Insult and Fever — COMPLETED · NA
• Approaches and Decisions for Acute Pediatric TBI Trial — COMPLETED
• Impact of Severe Brain Injury on Neuro-vascular and Endothelial Regulation of Peripheral Microcirculation. — OTHER
• The Effect of Closed Suction System on the Incidence of Ventilator-associated Pneumonia. — COMPLETED · NA
• Vestibular Rehabilitation and Severe Traumatic Brain Injury — COMPLETED · NA
• Randomized Control Trial to Compare Standard Monitoring and Plethysmographic Variability Index-Guided Fluid Therapy In 64 Severe Traumatic Brain Injury Patients, Aged 18 to 60 Years Old Undergoing Emergency Craniotomies — COMPLETED · NA
• Aquatic Sequential Preparatory Approach and Severe Traumatic Brain Injury — COMPLETED · NA
• Brain Tissue Oxygen Monitoring in Traumatic Brain Injury (TBI) — COMPLETED · PHASE2
• Identification of Predictive Neuroinflammatory Biomarkers of Neuro-radiological Evolution in Severe Traumatic Brain Injury — OTHER · NA
• Discrete Hypothermia in the Management of Traumatic Brain Injury — COMPLETED · PHASE3
• Study of the Safety and Efficacy of Conivaptan (Vaprisol®) to Raise Serum Sodium Levels in Patients With Severe Traumatic Brain Injury — COMPLETED · PHASE1
• Cortical Excitability in Patients With Severe Brain Injury — OTHER · NA
• Efficacy of Pharmacological Treatment of Working Memory Impairment After Traumatic Brain Injury: Evaluation With fMRI — OTHER · NA

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