Sickle Cell Anemia Clinical Trials

157 clinical trials for Sickle Cell Anemia across international registries, including 16 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias — RECRUITING · PHASE1
• A Long-term Follow-up Study in Participants Who Received CTX001 — RECRUITING · PHASE3
• Blood Sampling for Research Related to Sickle Cell Disease — RECRUITING
• Alendronate for Osteonecrosis in Adults With Sickle Cell Disease — RECRUITING · PHASE2
• Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation — RECRUITING
• Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin — RECRUITING · PHASE2
• Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease — RECRUITING · PHASE3
• Serial Assessment of Fertility Experiences — RECRUITING
• Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies — RECRUITING · PHASE1
• Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease — RECRUITING
• Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE) — RECRUITING · PHASE4
• Pressure Pain Tolerance in Relation to Balance and Strength in Children — RECRUITING · NA
• OPTIMA STUDY : OPTIMIZING HYDROXYUREA DOSAGE WITH PHARMAKOKINETIC IN PATIENTS SUFFERING OF MODERATE TO SEVERE SICKLE CELL ANEMIA. — RECRUITING
• A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD — RECRUITING · PHASE2
• A VITAMIN D INTERVENTION IN CHILDREN WITH SICKLE CELL DISEASE: A PILOT RANDOMISED CONTROLLED TRIAL — RECRUITING
• A PHASE 3, DOUBLE-BLIND, RANDOMIZED, EFFICACY AND SAFETY COMPARISON OF PRASUGREL AND PLACEBO IN PEDIATRIC PATIENTS WITH SICKLE CELL DISEASE — RECRUITING · PHASE3
• Study of efficacy, safety and tolerability of ACZ885 (canakinumab) in pediatric and young adult patients with sickle cell anemia. — TERMINATED · PHASE2
• Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease — ACTIVE_NOT_RECRUITING
• Hypoxic Red Blood Cells in Sickle Cell Anemia — NOT_YET_RECRUITING · NA
• Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia — COMPLETED
• Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease — NOT_YET_RECRUITING · PHASE1
• Dose Escalation Study of PF-07209326 in Healthy Participants and Participants With Sickle Cell Disease — COMPLETED · PHASE1
• Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease — NOT_YET_RECRUITING · NA
• Haploidentical PBMC Transplant for Severe Congenital Anemias — ACTIVE_NOT_RECRUITING · PHASE1
• Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia — ACTIVE_NOT_RECRUITING · PHASE1
• Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders — COMPLETED · NA
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Pociredir — COMPLETED · PHASE1
• The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease — COMPLETED · NA
• Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia — COMPLETED · PHASE2
• Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype — NOT_YET_RECRUITING · PHASE2
• The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC) — COMPLETED · NA
• A PHASE 2/3 RANDOMIZED, MULTICENTER STUDY OF OSIVELOTOR ADMINISTERED ORALLY TO ADULT AND ADOLESCENT PARTICIPANTS WITH SICKLE CELL DISEASE — NOT_YET_RECRUITING · PHASE2
• Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD) — SUSPENDED · NA
• Stroke Prevention in Young Adults With Sickle Cell Anemia — ACTIVE_NOT_RECRUITING
• Awake Prone Positioning for Severe Acute Chest Syndrome — NOT_YET_RECRUITING · NA
• Sickle Cell Disease (SCD) Bone Pain Study — ACTIVE_NOT_RECRUITING · NA
• SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia — COMPLETED · NA
• EXTEND EXpanding Treatment for Existing Neurological Disease — COMPLETED · PHASE2
• Full Assessment of Clinical Transfusion Support — COMPLETED
• Hydroxyurea Optimization Through Precision Study — COMPLETED · PHASE3
• Shared-Decision Making for Hydroxyurea — COMPLETED · NA
• Treatment of Sickle Cell Anemia With Stem Cell Transplant — TERMINATED · NA
• ERN-EuroBloodNet Registry on Patients With Rare Red Blood Cell Defects and COVID-19 — COMPLETED
• A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study — TERMINATED · PHASE3
• Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia — COMPLETED
• A Low-Interventional Study of an Electronic Sickle Cell Disease Patient Reported Outcomes in Sickle Cell Participants — TERMINATED
• Microvascular Blood Flow in Sickle Cell Anemia — COMPLETED · NA
• Hematopoietic Stem Cell Transplant for Sickle Cell Disease — COMPLETED · PHASE1
• The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria — COMPLETED
• At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions — COMPLETED

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