Sickle Cell Disease Clinical Trials

889 clinical trials for Sickle Cell Disease across international registries, including 158 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Blood Collection for Research Related to Certain Diseases Involving Blood Vessels — RECRUITING
• A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia — RECRUITING · PHASE3
• A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease — RECRUITING · PHASE3
• A Study to Provide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat Study — RECRUITING · PHASE4
• A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease — RECRUITING · PHASE2
• Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0 — RECRUITING · NA
• A Long-term Follow-up Study in Participants Who Received CTX001 — RECRUITING · PHASE3
• Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX) — RECRUITING
• Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants — RECRUITING
• Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System — RECRUITING
• Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD) — RECRUITING · PHASE2
• A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD) — RECRUITING · PHASE3
• A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) — RECRUITING · PHASE1
• Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease — RECRUITING · PHASE1
• The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease — RECRUITING · PHASE3
• Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors — RECRUITING · PHASE1
• Phase 2a, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety of Anumigilimab (CSL324) in Adults with Sickle Cell Disease — RECRUITING · PHASE2
• Blood Sampling for Research Related to Sickle Cell Disease — RECRUITING
• Cooperative Assessment of Late Effects for SCD Curative Therapies — RECRUITING
• Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease — RECRUITING · PHASE2
• A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) — RECRUITING · PHASE3
• Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease — RECRUITING · PHASE2
• A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease — RECRUITING · PHASE1
• Optimizing Hydroxyurea Therapy in Children With Sickle Cell Anemia In Malaria Endemic Areas: The NOHARM Maximum Tolerated Dose (MTD) Study — RECRUITING · PHASE1
• Alendronate for Osteonecrosis in Adults With Sickle Cell Disease — RECRUITING · PHASE2
• Early Life Exposures Among Children With Sickle Cell Disease — RECRUITING · NA
• Tocilizumab for Acute Chest Syndrome — RECRUITING · PHASE2
• ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders — RECRUITING
• Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease — RECRUITING · PHASE2
• mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria — RECRUITING · NA
• Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease — RECRUITING · PHASE1
• Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease — RECRUITING · PHASE1
• A Phase 1/2a, First-in-human, Randomized, Double-blinded, Placebo-controlled, Dose-finding Study in Healthy Volunteers and Participants with Sickle Cell Disease to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability, pH and Food Effect, and Preliminary Efficacy of BMS-986470 — RECRUITING · PHASE2
• Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease — RECRUITING · PHASE1
• Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease — RECRUITING
• Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease — RECRUITING · PHASE3
• Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation — RECRUITING
• Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA) — RECRUITING · NA
• Uganda Sickle Surveillance Study (US-3) — RECRUITING
• Investigation of the Genetics of Hematologic Diseases — RECRUITING
• Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study — RECRUITING · PHASE4
• Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease — RECRUITING
• Sickle Cell Clinical Research and Intervention Program — RECRUITING
• Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy — RECRUITING · NA
• Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease — RECRUITING · PHASE1
• Allo HSCT for High Risk Hemoglobinopathies — RECRUITING · PHASE2
• Functional Ovarian Reserve in Sickle Cell Disease — RECRUITING
• SCD Stem Cell Mobilization and Apheresis Using Motixafortide — RECRUITING · PHASE1
• A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) — RECRUITING · PHASE2
• Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease — RECRUITING · PHASE4

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