Single-ventricle Clinical Trials

47 clinical trials for Single-ventricle across international registries, including 13 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Venous Compression in Fontan — RECRUITING · NA
• Impact of Early Fortini Initiation on Growth and Interstage Outcomes in Infants With Single Ventricle Physiology — RECRUITING · NA
• Fontan Fitness Trial — RECRUITING · NA
• Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis — RECRUITING
• Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry — RECRUITING
• REHAB Fontan Failure: A Trial of Cardiac Rehabilitation — RECRUITING · NA
• Ventripoint Single Ventricle Study — RECRUITING · NA
• Cardiac Stem/Progenitor Cell Infusion in Univentricular Physiology (APOLLON Trial) — RECRUITING · PHASE3
• Transcatheter Fontan Stenting: Impact on Hepatic Stiffness and Exercise Capacity — RECRUITING
• Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts — RECRUITING · PHASE2
• NIRS in Congenital Heart Defects - Correlation With Echocardiography — RECRUITING
• An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease — RECRUITING
• Association of Near Infrared Spectroscopy With Interstage Outcomes — RECRUITING · NA
• PK/PD of Digoxin in Infants With SVHD — COMPLETED · PHASE1
• Characterizing the Effect of Dopamine on Markers of Lymph Re-circulation in Fontan-associated Protein-losing Enteropathy — TERMINATED
• Fibrosis and the Fontan — COMPLETED · PHASE1
• Re-Energize Fontan — COMPLETED · NA
• ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis — ACTIVE_NOT_RECRUITING
• Simple Non-invasive Breathing Device to Improve Pulmonary Flow Pusatility in Single Ventricle Post Fontan — COMPLETED · NA
• Virtual Remote Physiological Monitoring Program of Children With Heart Disease — COMPLETED · NA
• Use of Vasopressin Following the Fontan Operation — COMPLETED · PHASE2
• Hemodynamic, Vascular and Muscular Parameters of Exercise Capacity in Single-Ventricle Patients With Fontan Procedure — COMPLETED
• Inspiratory Muscle Therapy in Subjects With Fontan Circulations — COMPLETED · NA
• Correlation Between 3D Echocardiography and Cardiopulmonary Exercise Testing in Patients With Single Ventricle — COMPLETED
• Frailty in Children With Cardiac Disease — COMPLETED
• Enhanced External Counterpulsation in Patients With Fontan Circulation — COMPLETED · NA
• Efficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart Disease — WITHDRAWN · PHASE3
• Clinical Characteristics and Associations of the "Good Fontan" Patient — COMPLETED
• The Effect of Fontan Fenestration Closure on Hepatic Stiffness — COMPLETED
• Cardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise Training — COMPLETED · NA
• The PaTHS Descriptive Correlational Longitudinal Study — COMPLETED
• Colchicine in Postoperative Fontan Patients — TERMINATED · PHASE2
• Perioperative Treprostinil in Pediatric Patients Undergoing the Fontan Operation — TERMINATED · NA
• Exercise Capacity in Patients With Fontan Procedure — COMPLETED
• Transcoronary Infusion of Cardiac Progenitor Cells in Patients With Single Ventricle Physiology — COMPLETED · PHASE1
• Fontan Imaging Biomarkers (FIB) Study — COMPLETED
• Multimodality Biomarkers for Noninvasive Assessment of the Fontan Patient — OTHER · NA
• Redesigning the Care Journey of Patients With Single-ventricle Congenital Heart Disease — COMPLETED
• Effect of Carvedilol on Exercise Performance in Fontan Patients — COMPLETED · PHASE4
• Early Use of Vasopressin in Post-Fontan Management — COMPLETED · PHASE2
• Validation of Cardiac Magnetic Resonance Sequences in Patients With Single Ventricles — OTHER
• Diffuse Myocardial Fibrosis in Fontan Patients — COMPLETED
• Changes in Cerebral Oxygenation During Laparoscopy in Patients With Single Ventricle Anatomy — WITHDRAWN
• Improving Functional Capacity in Fontan Patients Through Inspiratory Muscle Training — COMPLETED · NA
• The Destination Therapy Evaluation for Failing Fontan Study — WITHDRAWN · NA
• Effect of Tadalafil on Exercise Capacity in Pediatric Fontan Patients — COMPLETED · PHASE1
• Single Ventricle Outcome — COMPLETED

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