Squamous Cell Carcinoma of Head and Neck Clinical Trials

146 clinical trials for Squamous Cell Carcinoma of Head and Neck across international registries, including 34 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study of MGC026 in Participants With Advanced Solid Tumors — RECRUITING · PHASE1
• A Study of DM005 in Patients With Advanced Solid Tumors — RECRUITING · PHASE1
• A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers — RECRUITING · NA
• A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma — RECRUITING · PHASE1
• App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy — RECRUITING · NA
• Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers — RECRUITING · PHASE3
• A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer — RECRUITING · PHASE3
• A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer — RECRUITING · PHASE1
• A Study of Sigvotatug Vedotin in Advanced Solid Tumors — RECRUITING · PHASE1
• A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors — RECRUITING · PHASE1
• 5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC — RECRUITING · PHASE2
• A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer — RECRUITING · PHASE1
• 5-Fluorouracil Response and Optimization STudy (The FROST Trial) — RECRUITING · PHASE2
• A Study Investigating the Efficacy and Safety of the Combination of Iparomlimab and Tuvonralimab With or Without Chemotherapy in Second-line and Subsequent Treatments for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma — RECRUITING · NA
• Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas — RECRUITING · PHASE1
• Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence — RECRUITING · PHASE2
• HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers — RECRUITING · NA
• A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) — RECRUITING · PHASE2
• Reduction in the Number of Chemotherapy Cycles in Combination With Pembrolizumab in First-line Treatment of PD-L1-positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinomas — RECRUITING · PHASE2
• Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors — RECRUITING · PHASE1
• Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers — RECRUITING · PHASE1
• Optimised Early Management of Squamous Cell Carcinoma of the Head and Neck Cancer — RECRUITING · NA
• Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma — RECRUITING
• A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma — RECRUITING · PHASE1
• Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors — RECRUITING · PHASE1
• 2 Courses of Concurrent Cisplatin Chemoradiotherapy After Surgery for High-risk Head and Neck Squamous Cell Carcinoma — RECRUITING · PHASE3
• Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma — RECRUITING · PHASE2
• A Beta-only IL-2 ImmunoTherapY Study — RECRUITING · PHASE1
• Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck — RECRUITING
• Quantifying Systemic Immunosuppression to Personalize Cancer Therapy — RECRUITING
• European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] — RECRUITING · PHASE2
• Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study — RECRUITING · PHASE2
• Dose De-escalation and Sentinel LN Mapping Driven Radiotherapy of Contralateral Neck in Ipsilateral Node Positive HNSCC — RECRUITING · NA
• Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors — RECRUITING · PHASE2
• Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19) — TERMINATED · PHASE1
• Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination — ACTIVE_NOT_RECRUITING · NA
• Pilot Study of Imatinib Cetuximab Combo for H & N Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors. — NOT_YET_RECRUITING · PHASE2
• HYPORT: A Phase I/II Study of Hypofractionated Post-operative Radiation Therapy for Head and Neck Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck — COMPLETED · PHASE2
• Trial of a Personalized and Adaptive Neoantigen Dose-Adjusted Vaccine Concurrently With Pembrolizumab — SUSPENDED · PHASE1
• Phase II Study of Ficerafusp Alfa in Combination With Nivolumab in Patients With Platinum-refractory Head and Neck Squamous Cell Carcinoma — NOT_YET_RECRUITING · PHASE2
• Cetuximab Combined With Pembrolizumab or Finotonlimab and Chemotherapy in R/M HNSCC — NOT_YET_RECRUITING · PHASE3
• Camrelizumab in Combination With Cetuximab and Chemotherapy for Relapsed/Metastatic HNSCC Patients — COMPLETED · PHASE2
• TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC — ACTIVE_NOT_RECRUITING · PHASE1
• Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer — TERMINATED · PHASE1
• Using MASL to Combat Oral Cancer — COMPLETED · PHASE1
• MicroRNA Markers in Head and Neck Cancers — ACTIVE_NOT_RECRUITING
• A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors — TERMINATED · PHASE1
• Neoadjuvant Chemoimmunotherapy (Camrelizumab + Paclitaxel + Carboplatin) for Resectable HNSCC — NOT_YET_RECRUITING · PHASE2

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