Stage IV Breast Cancer Clinical Trials

203 clinical trials for Stage IV Breast Cancer across international registries, including 3 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer — RECRUITING · PHASE2
• A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer — RECRUITING · PHASE1
• Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer — RECRUITING · NA
• Surgery vs. No Surgery for Primary Tumor in De Novo Stage IV Breast Cancer With Solitary Bone Metastases — NOT_YET_RECRUITING · NA
• Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate Cancer — COMPLETED · PHASE1
• Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU — TERMINATED · PHASE3
• Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer — COMPLETED · PHASE2
• Pertuzumab, Trastuzumab, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With HER2-Positive Advanced Breast Cancer — COMPLETED · PHASE2
• Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer — ACTIVE_NOT_RECRUITING · PHASE2
• Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer — COMPLETED · PHASE2
• Vaccine Therapy in Treating Patients With HER2-Negative Stage III-IV Breast Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• Copper Cu 64-DOTA-Trastuzumab PET in Predicting Response to Treatment With Ado-Trastuzumab Emtansine in Patients With Metastatic HER2 Positive Breast Cancer — ACTIVE_NOT_RECRUITING · NA
• Window of Opportunity Study Targeting the Inflammatory Milieu — COMPLETED · PHASE1
• Positron Emission Tomography in Women With Advanced HER2-Positive Breast Cancer — ACTIVE_NOT_RECRUITING · NA
• Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy — ACTIVE_NOT_RECRUITING · PHASE3
• Romidepsin and Abraxane in Treating Patients With Metastatic Inflammatory Breast Cancer — TERMINATED · PHASE1
• Investigational Drug in Combination With Two Chemotherapy Drugs in Women With Locally Recurrent or Metastatic Breast Cancer — WITHDRAWN · PHASE1
• Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer — COMPLETED · PHASE1
• Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer — COMPLETED · NA
• Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer — TERMINATED · NA
• Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer — COMPLETED · PHASE2
• Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs — WITHDRAWN
• Mindfulness-Based Stress Reduction in Helping Participants With Metastatic Breast Cancer — COMPLETED · NA
• Hypofractionated Image Guided Radiation Therapy in Treating Patients With Stage IV Breast Cancer — COMPLETED
• BYL719 and Letrozole in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast Cancer — OTHER · PHASE1
• Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab — COMPLETED · PHASE1
• Clinical Study of Personalized Chemotherapy for Breast Cancer With Low Doses of Cyclophosphamide — OTHER · PHASE1
• Ultrasound in Detecting Taxane-Induced Neuropathy in Patients With Breast Cancer — COMPLETED · NA
• Pembrolizumab and Doxorubicin Hydrochloride or Anti-Estrogen Therapy in Treating Patients With Triple-Negative or Hormone Receptor-Positive Metastatic Breast Cancer — COMPLETED · PHASE2
• Sorafenib in Treating Patients With Metastatic Breast Cancer — COMPLETED · PHASE2
• Compare the Efficacy of Surgery Combined With Systemic Therapy and Pure Systemic Therapy in Breast Cancer Patients — WITHDRAWN · PHASE2
• Galunisertib and Paclitaxel in Treating Patients With Metastatic Androgen Receptor Negative (AR-) Triple Negative Breast Cancer — COMPLETED · PHASE1
• Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer — OTHER · NA
• Medroxyprogesterone +/- Cyclophosphamide & Methotrexate in Hormone Receptor-Negative Recurrent/Metastatic Breast Cancer — COMPLETED · PHASE2
• Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors — COMPLETED · PHASE1
• Capecitabine, Cyclophosphamide, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With HER2-Positive Metastatic Breast Cancer — TERMINATED · PHASE2
• Ask Questions (ASQ):Implementation of a Communication Intervention — COMPLETED · NA
• PET/CT in Evaluating Response to Chemotherapy in Patients With Breast Cancer — TERMINATED · NA
• Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer — COMPLETED · PHASE2
• Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer — COMPLETED · NA
• Vaccine Therapy With or Without Polysaccharide-K in Patients With Stage IV HER2 Positive Breast Cancer Receiving HER2-Targeted Monoclonal Antibody Therapy — COMPLETED · PHASE1
• Viral Therapy In Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer or Metastatic Breast Cancer — COMPLETED · PHASE1
• G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancer — COMPLETED · PHASE1
• Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery — COMPLETED · PHASE1
• Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian Cancer — COMPLETED · PHASE1
• S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER) — COMPLETED · NA
• 4-1BB Agonist Monoclonal Antibody PF-05082566 With Trastuzumab Emtansine or Trastuzumab in Treating Patients With Advanced HER2-Positive Breast Cancer — COMPLETED · PHASE1
• Copanlisib, Letrozole, and Palbociclib in Treating Patients With Hormone Receptor Positive HER2 Negative Stage I-IV Breast Cancer — TERMINATED · PHASE1
• Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancer — TERMINATED · PHASE1
• Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer — COMPLETED · PHASE1

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