Stage IV Non-small Cell Lung Cancer Clinical Trials

170 clinical trials for Stage IV Non-small Cell Lung Cancer across international registries, including 7 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer — RECRUITING · NA
• A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer — RECRUITING · PHASE1
• Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC — RECRUITING · PHASE1
• Patient-centered, Optimal Integration of Survivorship and Palliative Care — RECRUITING · NA
• PALACE: Cemiplimab Trial According to ctDNA Levels — RECRUITING · PHASE2
• Analysis of Circulating Tumor DNA Dynamics to Predict and Monitor Response to TKI in Patients With Advanced NSCLC. — RECRUITING
• Heterogeneously Hypofractionated Radiotherapy for Locally Advanced NSCLC — RECRUITING · NA
• Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer — ACTIVE_NOT_RECRUITING · NA
• Ruxolitinib for Cancer Cachexia — ACTIVE_NOT_RECRUITING · PHASE1
• Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate Cancer — COMPLETED · PHASE1
• Study of Crizotinib for ROS1 and MET Activated Lung Cancer — COMPLETED · PHASE2
• Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer — ACTIVE_NOT_RECRUITING · PHASE2
• S1403, Afatinib Dimaleate With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung Cancer — COMPLETED · PHASE2
• Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC — ACTIVE_NOT_RECRUITING · PHASE1
• Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• Study of ONO-7475 in Combination With Osimertinib in EGFR Gene Mutation-positive Non-small Cell Lung Cancer — COMPLETED · PHASE1
• Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases — COMPLETED · PHASE1
• CISH Inactivated TILs in the Treatment of NSCLC — WITHDRAWN · PHASE1
• Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer — TERMINATED · PHASE1
• Peripheral Blood ETASTs for Predicting Efficacy of Chemoimmunotherapy in NSCLC — NOT_YET_RECRUITING
• TG4010 and Nivolumab in Patients With Lung Cancer — COMPLETED · PHASE2
• Radical RADiotherapy and Immunotherapy for Metastatic CAncer of the Lung (RRADICAL) — COMPLETED · NA
• Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475 — COMPLETED · PHASE2
• Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments — ACTIVE_NOT_RECRUITING
• Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer — COMPLETED · PHASE1
• A Phase 3, Multicenter, Randomized, Double-Blind Study of MK-7684 with Pembrolizumab as a Coformulation (MK-7684A) Versus Pembrolizumab Monotherapy as First Line Treatment for Participants With PD-L1 Positive Metastatic Non-Small Cell Lung Cancer (KEYVIBE-003) — OTHER · PHASE3
• Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography — COMPLETED · NA
• Naloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer — TERMINATED · PHASE2
• A Phase 2 Precision Oncology Study of Biomarker-Directed, Pembrolizumab- (MK-3475, SCH 900475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (KEYNOTE-495; KeyImPaCT) — OTHER · PHASE2
• Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer — COMPLETED
• Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer — TERMINATED · PHASE1
• Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer — COMPLETED · NA
• A Phase 3, Randomized Study of Nivolumab plus Ipilimumab in Combination with Chemotherapy vs Chemotherapy alone as First Line Therapy in Stage IV Non-Small Cell Lung Cancer (NSCLC) — OTHER · PHASE3
• Pembrolizumab and Afatinib in Patients With Non-small Cell Lung Cancer With Resistance to Erlotinib — COMPLETED · PHASE1
• Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors — COMPLETED · PHASE1
• Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic Mutations — TERMINATED · PHASE2
• Pembrolizumab Alone or Sequentially Following Single Fraction Non-ablative Radiation to One of the Target Lesions, in Previously Treated Patients With Stage IV NSCLC — COMPLETED · PHASE2
• FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer — COMPLETED · PHASE2
• PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer — COMPLETED · PHASE2
• Effect of Pembrolizumab With or Without Carboplatin and Paclitaxel on Immune Response in Patients With Recurrent or Stage IIIB-IV Non-small Cell Lung Cancer — COMPLETED · PHASE2
• Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer — COMPLETED · PHASE2
• Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer — OTHER · NA
• Pemetrexed Disodium in Treating Patients With Stage IV Non-small Cell Lung Cancer and ECOG Performance Status 3 — COMPLETED · PHASE2
• Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors — COMPLETED · PHASE1
• Nimotuzumab and Nivolumab in Treating Patients With Advanced Non-small Cell Lung Cancer — COMPLETED · PHASE1
• Vinorelbine Tartrate and Paclitaxel in Treating Older Patients With Advanced Non-Small Cell Lung Cancer — COMPLETED · PHASE2
• Study of Anti-Epidermal Growth Factor Receptor (EGFr) Antibody, Cetuximab, in Combination With Gemcitabine/Carboplatin in Patients With Stage IV Lung Cancer — COMPLETED · PHASE1
• Maintenance Chemotherapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Chemotherapy for Stage IV Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II Trial — COMPLETED · PHASE2
• Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors — WITHDRAWN · PHASE1
• KN046 in Patients With Advanced Non-small Cell Lung Cancer — TERMINATED · PHASE2

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