Thrombotic Thrombocytopenic Purpura Clinical Trials

44 clinical trials for Thrombotic Thrombocytopenic Purpura across international registries, including 8 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study in Children and, Adults With Congenital Thrombotic Thrombocytopenic Purpura (cTTP) Treated With Adzynma — RECRUITING
• Immunological Aspect of Thrombotic Thrombocytopenic Purpura (TTP) — RECRUITING
• A Survey of Recombinant ADAMTS13 in Participants With Congenital Thrombotic Thrombocytopenic Purpura — RECRUITING
• Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center — RECRUITING
• Longitudinal Cohort of Thrombosis and Hemostasis Diseases — RECRUITING
• Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome) — RECRUITING
• AN OPEN-LABEL, SINGLE-ARM, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CAPLACIZUMAB AND IMMUNOSUPPRESSIVE THERAPY WITHOUT FIRST-LINE THERAPEUTIC PLASMA EXCHANGE IN ADULTS WITH IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA — RECRUITING
• "A PHASE 2, MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY IN PATIENTS WITH ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA (ATTP) TO EVALUATE THE PHARMACOKINETICS, SAFETY, AND EFFICACY OF RADAMTS-13 (SHP655) ADMINISTERED IN ADDITION TO STANDARD OF CARE (SOC) TREATMENT." — RECRUITING · PHASE2
• A Study to Learn More About the Treatment of People With Congenital Thrombotic Thrombocytopenic Purpura (cTTP) Who Received Recombinant ADAMTS13 (rADAMTS13) as Part of the Early Access Program — NOT_YET_RECRUITING
• A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP) — COMPLETED · PHASE2
• A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura — ACTIVE_NOT_RECRUITING · PHASE3
• A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP) — COMPLETED · PHASE3
• Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura — COMPLETED · PHASE3
• A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP) — COMPLETED · PHASE2
• Expanded Access Program of TAK-755 for Congenital Thrombotic Thrombocytopenic Purpura (cTTP) — OTHER
• An open-label, single-arm, multicenter study to evaluate the efficacy and safety of caplacizumab and immunosuppressive therapy without first-line therapeutic plasma exchange in adults with immunemediated thrombotic thrombocytopenic purpura — OTHER · PHASE3
• Safety Study of Danazol With Plasma Exchange and Steroids for the Treatment of Thrombotic Thrombocytopenic Purpura (TTP) — TERMINATED · PHASE2
• At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions — COMPLETED
• A Prospective Study on the Long-Term Vascular Burden in Thrombotic Thrombocytopenic Purpura Patients — OTHER
• The Use of Rituximab in Acute Thrombotic Thrombocytopenic Purpura (TTP) — COMPLETED · PHASE2
• Study of Cyclosporine or Corticosteroids as an Adjunct to Plasma Exchange in Thrombotic Thrombocytopenic Purpura (TTP) — COMPLETED · PHASE3
• SABRE: A Single-arm Prospective Study Measuring Safety and Tolerability of SARS-CoV-2 Neutralising Antibodies in High-risk Populations — WITHDRAWN · PHASE2
• A Retrospective, Observational Study on the Response to Caplacizumab Treatment in aTTP Patients: the Italian Experience (ROSCAPLI) — OTHER
• Aspirin for Prophylaxis of TTP — NOT_YET_RECRUITING · PHASE2
• .German TTP-Registry (Thrombotic Thrombocytopenic Purpura) — OTHER
• Magnesium Sulfate in Thrombotic Thrombocytopenic Purpura in Intensive Care — OTHER · PHASE3
• Low Dose Rituximab in Thrombotic Thrombocytopenic Purpura — COMPLETED · PHASE2
• The ConNeCT Study: Neurological Complications of TTP — OTHER
• Observational Study of the Use of octaplasLG®. — COMPLETED
• Romiplostim, Rituximab and Dexamethasone as Frontline Treatment for Immune Thrombocytopenia — OTHER · PHASE2
• Octaplas Adult TTP Trial — TERMINATED
• Early Predictive Factors of Cardiac and Cerebral Involvement in TMA — COMPLETED · NA
• The Role of Microparticles as a Biomarker — WITHDRAWN
• TTP and aHUS in Complicated Pregnancies — OTHER
• A PHASE 3, PROSPECTIVE, RANDOMIZED, CONTROLLED, OPEN-LABEL, MULTICENTER, 2-PERIOD CROSSOVER STUDY WITH A SINGLE ARM CONTINUATION EVALUATING THE SAFETY AND EFFICACY OF BAX930 (RADAMTS13) IN PROPHYLACTIC AND ON-DEMAND TREATMENT OF SUBJECTS WITH SEVERE CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA (CTTP, UPSHAW-SCHULMAN SYNDROME [USS], HEREDITARY THROMBOTIC THROMBOCYTOPENIC PURPURA [HTTP]) — NOT_YET_RECRUITING · PHASE3
• Safety and Efficacy Study to Compare Uniplas With Cryosupernatant Plasma in Thrombotic Thrombocytopenic Purpura (TTP) — TERMINATED · PHASE3
• A PHASE III DOUBLE-BLIND, RANDOMIZED, PARALLEL GROUP, MULTICENTER PLACEBO-CONTROLLED TRIAL TO STUDY THE EFFICACY AND SAFETY OF CAPLACIZUMAB IN PATIENTS WITH ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA — COMPLETED · PHASE3
• Rituximab in Adult Acquired Idiopathic Thrombotic Thrombocytopenic Purpura — COMPLETED · PHASE2
• Evaluating the Effectiveness of Adding Rituximab to Standard Treatment for Thrombotic Thrombocytopenic Purpura (TTP) — TERMINATED · PHASE3
• International Registry and Biorepository for TMA(Thrombotic Microangiopathy) — TERMINATED
• ADAMTS13 in Thrombotic Thrombocytopenic Purpura — COMPLETED
• Use of Rituximab Treatment in Addition to Standard Care for Newly Presenting Thrombotic Thrombocytopenic Purpura — WITHDRAWN · PHASE1
• Rituximab in Patients With Relapsed or Refractory TTP-HUS — OTHER · PHASE2
• Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy — TERMINATED · PHASE2

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