Transfusion-dependent Beta-Thalassemia Clinical Trials

21 clinical trials for Transfusion-dependent Beta-Thalassemia across international registries, including 9 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT) — RECRUITING · PHASE3
• Gene-Modified Stem Cell Therapy for Subjects With Transfusion-dependent Beta-thalassemia — RECRUITING · PHASE2
• Use of the Hemanext One® Hypoxic Red Blood Cell Storage System for Transfusion in Thalassemia Patients — RECRUITING
• Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients — RECRUITING · NA
• A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301 — RECRUITING
• Β-Thalassemia Treatment with KL003 Cell Injection — RECRUITING · PHASE1
• Decision-Making and Quality of Life Surrounding Hematologic Disease and Gene Therapy — RECRUITING
• Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene Therapy — RECRUITING
• A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent β-Thalassemia [TDT] — RECRUITING · PHASE1
• A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT) — ACTIVE_NOT_RECRUITING · PHASE3
• A single arm, open label, multicenter, single-dose, phase 2b clinical study evaluating efficacy and safety of gene therapy using autologous CD34+ hematopoietic stem cells transduced with the GLOBE lentiviral vector using an improved transduction protocol in subjects with transfusion-dependent beta-thalassemia. — TERMINATED · PHASE2
• Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia — COMPLETED · PHASE2
• Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia — COMPLETED · PHASE4
• Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent Thalassemia — COMPLETED · PHASE2
• Evaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalassemia. — ACTIVE_NOT_RECRUITING · NA
• Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy — ACTIVE_NOT_RECRUITING
• EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT) — ACTIVE_NOT_RECRUITING · PHASE1
• A Pilot Study on the Safety and Efficacy of YOLT-204 for Transfusion-Dependent Beta-Thalassemia — NOT_YET_RECRUITING · PHASE1
• Plasticizer Exposure and Its Consequences on Health — NOT_YET_RECRUITING
• A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT) — COMPLETED · PHASE1
• Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients — COMPLETED · PHASE3

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