Transthyretin Amyloidosis Clinical Trials

47 clinical trials for Transthyretin Amyloidosis across international registries, including 9 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant — RECRUITING · PHASE3
• Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis — RECRUITING · PHASE4
• Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis — RECRUITING
• The Eplontersen Pregnancy and Lactation Outcomes Study — RECRUITING
• Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy — RECRUITING · NA
• Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis — RECRUITING · PHASE2
• ATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, Turkey — RECRUITING
• Phenotyping and Characterization of wtATTR-CM (TRACE 1) — RECRUITING
• Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF — RECRUITING · NA
• AN OPEN LABEL EXTENSION STUDY TO EVALUATE THE SAFETY AND EFFICACY OF DIFLUNISAL IN TRANSTHYRETIN HEREDITARY AMYLOIDOSIS — COMPLETED · PHASE2
• A Phase 3, Randomized, Multicenter, Double-Blind, Placebo-Controlled Study of Acoramidis for Transthyretin Amyloidosis Prevention in the Young (ACT-EARLY Trial) — TERMINATED · PHASE3
• Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations — NOT_YET_RECRUITING
• Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy — COMPLETED · PHASE1
• Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA) — NOT_YET_RECRUITING
• Expanding the Biomarkers in Familial Amyloid Neuropathy: MRI and Motor Unit Estimation by Electrophysiological Study — COMPLETED · NA
• A Study to Establish the Bioequivalence of Free Acid Tafamidis 61 mg Capsule and Tablet, and Evaluate the Safety and Tolerability of the 61 mg Tablet in Healthy Adults Under Fed Conditions — OTHER · PHASE1
• A Phase 3, Open-Label, Multicenter, Extension Study of Acoramidis in Patients with Newly Diagnosed Variant Transthyretin Amyloid Cardiomyopathy (ACT-EARLY OLE) — NOT_YET_RECRUITING · PHASE3
• Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis — COMPLETED
• HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis) — COMPLETED · PHASE3
• Myocardial Effects in Patients With ATTRv With Polyneuropathy Treated With Patisiran or Vutrisiran — ACTIVE_NOT_RECRUITING
• Evaluation of a Claims-based Algorithm for the Identification of Transthyretin-mediated Amyloidosis (ATTR) Amyloidosis in Medical Records — WITHDRAWN · PHASE1
• Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery — COMPLETED · NA
• Evuzamitide in PET/CT to Measure Potential Therapeutic Response in ATTR — COMPLETED · PHASE2
• TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects — COMPLETED
• A study to establish the bioequivalence of free acid tafamidis 61 mg capsule and tablet, and evaluate the safety and tolerability of the 61 mg tablet in healthy adults — OTHER · PHASE1
• PL_GNT01_ISR_Grant 53234273 — OTHER
• Transthyretin Amyloidosis Outcome Survey (THAOS) — COMPLETED
• Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis — COMPLETED · PHASE1
• Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy — COMPLETED · PHASE3
• Positron Emission Tomography / Magnetic Resonance Imaging in Aortic Stenosis — COMPLETED
• Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver Transplant — COMPLETED · PHASE3
• New Biomarkers and Plasma Prothrombotic Potential in Cardiac Transthyretin Amyloidosis — OTHER
• Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surgery — TERMINATED
• Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese Population — OTHER
• The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis. — OTHER
• Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP) — WITHDRAWN
• Study of Cerebral MRI Anomalies in Mutated Transthyretin Amyloidosis Patients — COMPLETED
• Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology — COMPLETED · NA
• Screening for Systemic Amyloidosis Via the Ligamentum Flavum — COMPLETED
• Carpal Tunnel Syndrome and Amyloid Cardiomyopathy — COMPLETED
• Cardiac Amyloidosis Screening at Trigger Finger Release — COMPLETED
• The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy Patients — OTHER · PHASE4
• ATTR-Cardiomyopathy Stabilization Following Tafamidis Therapy — OTHER
• Patient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin Amyloidosis — OTHER
• Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR) — COMPLETED · PHASE1
• Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis — COMPLETED · PHASE2
• Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis — COMPLETED · PHASE2

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