Treatment Resistant Depression Clinical Trials

314 clinical trials for Treatment Resistant Depression across international registries, including 77 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

Natural History of Depression, Bipolar Disorder and Suicide Risk — RECRUITING
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression — RECRUITING · PHASE3
ipRGC as a Potential Biomarker for Predicting Transcranial Magnetic Stimulation Treatment Response in Major Depressive Disorder — RECRUITING · NA
Lumateperone for Late-Life Depression — RECRUITING · PHASE3
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST) — RECRUITING · PHASE2
Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression — RECRUITING · PHASE2
Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression — RECRUITING · NA
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND) — RECRUITING · PHASE2
Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression — RECRUITING · NA
Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression — RECRUITING · NA
Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients — RECRUITING
Cannabidiol Oil for Treatment-Resistant Major Depression — RECRUITING · PHASE1
An Open-Label Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression — RECRUITING · PHASE2
Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression — RECRUITING · PHASE1
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND) — RECRUITING · NA
Treatment Resistant Depression and Vagus Nerve Stimulation — RECRUITING · NA
DBS for TRD With the Medtronic Percept PC — RECRUITING · NA
Transcranial Ultrasonic Stimulation in Treatment-resistant Depression : an Open-label Pilot Trial — RECRUITING · NA
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression — RECRUITING · NA
DBS for Depression — RECRUITING · PHASE1
Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression — RECRUITING · PHASE4
A Comparison of Two Psychotherapy Programs in Persistently Depressed Treatment-Resistant Inpatients — RECRUITING · NA
Accelerated iTBS for Major Depression — RECRUITING · NA
Ketamine Augmentation of ECT in Treatment-Resistant Depression — RECRUITING · PHASE3
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA) — RECRUITING · PHASE2
Mindfulness Engaged Neurostimulation for Depression (MEND II) — RECRUITING · PHASE2
Transcranial Photobiomodulation (tPBM) for Somatic Symptoms in Treatment-Resistant Depression — RECRUITING · NA
Maintenance rTMS for Depression (Maitr-De) — RECRUITING · NA
ALTO-207 in Adults With Treatment-resistant Depression (TRD) — RECRUITING · PHASE2
Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression — RECRUITING · PHASE4
Personalized DBS Targeting for Treating Depression — RECRUITING · PHASE1
Belief Updating in Treatment Resistant Depression — RECRUITING
Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression — RECRUITING
Characterizing Dopamine Receptor Binding in Treatment Resistant Depression — RECRUITING
Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy — RECRUITING
University of Iowa Interventional Psychiatry Service Patient Registry — RECRUITING
40 Hz Light Neurostimulation for Patients With Depression (FELIX) — RECRUITING · NA
Ultrasound Neuromodulation of Circuits and Negative Valence Systems in Treatment-Resistant Depression — RECRUITING · NA
Biomarker-guided rTMS for Treatment Resistant Depression — RECRUITING · PHASE3
Esketamine With or Without Integration Therapy for Treatment-Resistant Depression — RECRUITING · PHASE4
A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression. — RECRUITING
COpenhagen Magnetic Personalized Accelerated Brain Circuit Therapy for Treatment Resistant Depression — RECRUITING · NA
PCS in Severe Treatment Resistant Depression — RECRUITING · NA
Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study — RECRUITING · NA
Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression — RECRUITING · NA
Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression — RECRUITING · NA
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial — RECRUITING · PHASE2
Comparison of the Efficacy of Accelerated Intermittent Theta Burst Stimulation and Accelerated Continuous Theta Burst Stimulation in Patients With Treatment-Resistant Depression — RECRUITING · NA
Psilocybin rTMS for Treatment Resistant Depression — RECRUITING · PHASE2
Psilocybin Microdosing With Psychotherapy for Treatment-Resistant Depression — RECRUITING · PHASE2

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