A RANDOMIZED PHASE II TRIAL ASSESSING TRIMODALITY THERAPY WITH OR WITHOUT ADJUVANT DURVALUMAB TO TREAT PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER

Registry ID

BL13

Source registry

HEALTH_CANADA

Status

Ongoing

Phase

PHASE2

Study type

INTERVENTIONAL

Sponsor

CANADIAN CANCER TRIALS GROUP, CANCER RESEARCH INSTITUTE, QUEEN'S UNIVERSITY

Start date

2020-03-09

Last update

2018-12-21

Conditions

• MUSCLE-INVASIVE BLADDER CANCER

Related clinical trials

• AN OPEN-LABEL, SINGLE-ARM, GLOBAL STUDY OF PERIOPERATIVE DURVALUMAB WITH CISPLATIN-BASED NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER (NIAGARA-2)
• A PHASE 3, RANDOMIZED, OPEN-LABEL STUDY TO EVALUATE PERIOPERATIVE ENFORTUMAB VEDOTIN PLUS PEMBROLIZUMAB (MK-3475) VERSUS NEOADJUVANT GEMCITABINE AND CISPLATIN IN CISPLATIN-ELIGIBLE PARTICIPANTS WITH MUSCLE-INVASIVE BLADDER CANCER (KEYNOTE-B15 /EV-304)
• A PHASE 3 RANDOMIZED STUDY OF CYSTECTOMY PLUS PERIOPERATIVE PEMBROLIZUMAB VERSUS CYSTECTOMY ALONE IN CISPLATIN-INELIGIBLE PARTICIPANTS WITH MUSCLE-INVASIVE BLADDER CANCER (KEYNOTE-905)

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