A PHASE I, OPEN-LABEL, MULTICENTRE STUDY TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PRELIMINARY ANTI-TUMOUR ACTIVITY OF ASCENDING DOSES OF AZD8186 IN PATIENTS WITH ADVANCED CASTRATE-RESISTANT PROSTATE CANCER (CRPC), SQUAMOUS NON-SMALL CELL LUNG CANCER (SQNSCLC), TRIPLE NEGATIVE BREAST CANCER (TNBC) AND PATIENTS WITH KNOWN PTEN-DEFICIENT ADVANCED SOLID MALIGNANCIES, WITH EXPANSION TO ASSESS THE PHARMACODYNAMIC ACTIVITY OF AZD8186 WITHIN PROSPECTIVELY-VALIDATED PTEN DEFICIENT TUMOURS
- Registry ID
- D4620C00001
- Source registry
- HEALTH_CANADA
- Status
- Closed
- Phase
- PHASE1
- Study type
- INTERVENTIONAL
- Sponsor
- ASTRAZENECA CANADA INC
- Completion date
- 2020-02-07
- Last update
- 2013-06-06
Conditions
- MALIGNANT SOLID TUMOURS
- NON-SMALL CELL LUNG CANCER
- PROSTATE CANCER
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