A PHASE III, OPEN-LABEL, RANDOMISED, MULTICENTRE, GLOBAL STUDY OF ADJUVANT DATOPOTAMAB DERUXTECAN IN COMBINATION WITH RILVEGOSTOMIG IN PARTICIPANTS WITH HIGH-RISK MUSCLE INVASIVE UROTHELIAL CARCINOMA (TROPION-UROTHELIAL04)

Registry ID

D763TC00001

Source registry

HEALTH_CANADA

Status

Ongoing

Phase

PHASE3

Study type

INTERVENTIONAL

Sponsor

ASTRAZENECA CANADA INC

Start date

2026-07-06

Last update

2026-05-22

Conditions

• UROTHELIAL CANCER

Related clinical trials

• A PHASE 3, RANDOMIZED, OPEN-LABEL STUDY OF SACITUZUMAB TIRUMOTECAN (MK-2870) CARCINOMA VERSUS INVESTIGATOR’S CHOICE OF NON-PLATINUM CHEMOTHERAPY IN PARTICIPANTS WITH PRETREATED LOCALLY ADVANCED/METASTATIC UROTHELIAL
• IZABRIGHT-BLADDER01: A RANDOMIZED, OPEN-LABEL, PHASE 2/3 TRIAL OF IZALONTAMAB BRENGITECAN VERSUS PLATINUM-BASED CHEMOTHERAPY FOR METASTATIC UROTHELIAL CANCER IN PARTICIPANTS WITH DISEASE PROGRESSION ON OR AFTER AN IMMUNOTHERAPY-BASED TREATMENT
• A PHASE 1/2, SINGLE-ARM, OPEN-LABEL TRIAL TO EVALUATE THE SAFETY AND EFFICACY OF NADOFARAGENE FIRADENOVEC INSTILLED TO THE RENAL PELVIS IN ADULT SUBJECTS WITH LOW-GRADE UPPER TRACT UROTHELIAL CARCINOMA (LG-UTUC)
• MODERN: AN INTEGRATED PHASE 2/3 AND PHASE 3 TRIAL OF MRDBASED OPTIMIZATION OF ADJUVANT THERAPY IN UROTHELIAL CANCER
• A RANDOMIZED OPEN-LABEL PHASE 2/3 STUDY OF BT8009 AS MONOTHERAPY OR IN COMBINATION IN PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER (DURAVELO-2)
• A PHASE 2/3 MULTICENTER TRIAL EVALUATING THE SAFETY AND EFFICACY OF ST-02 ON ABLATION OF UROTHELIAL CARCINOMAS IN THE UPPER URINARY TRACT

View on source registry