Changes in gambling severity, stress response and epigenetic regulation of the oxytocin and dopamine system in gambling addiction before and after metacognitive training

Registry ID
DRKS00039438
Source registry
DRKS
Status
RECRUITING
Study type
INTERVENTIONAL
Sponsor
Medizinische Hochschule Hannover
Enrollment
90
Last update
2026-08-14

Conditions

Inclusion criteria

Patients: - age ≥ 18 years - diagnosis of "gambling disorder" according to DSM-5 - gambling behavior anytime during the last 28 days Healthy controlls: - age ≥ 18 years

Exclusion criteria

Patients: - age < 18 years - insuffienct knowledge of the German language - excessive gambling during a psychotic or manic episode - inability to give informed consent - substance-related addiction except tobacco Healthy controls: - age below 18 years - substance-related addiction except tobacco, mental disorders - inability to give informed consent - no subordination/dependency to the study personel

Primary outcomes

1. Symptom severity assesed with the PGYBOCS at the first timepoint and three months after finishing group therapy

Locations

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