A Double-Blind, Randomized, Multicenter Study to Evaluate the Safety, Tolerability, and Immunogenicity of ZOSTAVAX™ Administered Concomitantly Versus Nonconcomitantly with Influenza Virus Vaccine (Inactivated)

Registry ID
EUCTR2005-003035-52
Source registry
EUCTR
Status
Completed
Phase
PHASE3
Sponsor
Merck & Co. Inc.
Start date
2005-10-06
Last update
2026-08-16

Conditions

Summary

1) To determine whether ZOSTAVAX™ administered concomitantly with influenza vaccine in subjects 50 years of age or older elicits a VZV antibody response that is noninferior to that of ZOSTAVAX™ administered alone. 2) To demonstrate whether ZOSTAVAX™ elicits an acceptable VZV antibody response when administered concomitantly with influenza vaccine in subjects 50 years of age or older. 3) To assess whether influenza vaccine administered concomitantly with ZOSTAVAX™ in subjects 50 years of age or older elicits strain-specific influenza antibody responses that are noninferior to those of influenza vaccine administered alone.

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