Comparison of Pertussis Specific Cellular and Humoral Immunity Before and After a Acellular Pertussis Booster-Vaccineation in Combination With a Diphtheria-Tetanus-Polio-Vaccine Between Three Groups of Adolescents 10-14 Years of Age That Have Previously Either Received 4 or 5 Doses of Acellular Pertussis Vaccine or 4 Doses of of Whole-Cell Pertussis Vaccine

Registry ID
EUCTR2005-005532-27
Source registry
EUCTR
Status
Completed
Phase
PHASE4
Sponsor
Sanofi Pasteur Inc.
Start date
2006-02-01
Completion date
2006-10-31
Last update
2026-08-16

Conditions

Summary

Evaluation of the pertussis-specific humoral and cellular immunity after vaccination with REPEVAX® or COVAXiS® or COVAXiS® + IPV Merieux® among three groups: Group A: Adolescents 10-14 years of age who participated in study 371-03/01 and therefore have already received five doses of acellular pertussis vaccine and that simultaneously participate in the TRI05 study where they receive either REPEVAX® or COVAXiS® + IPV Merieux® depending on their randomization group. Group B: Adolescents 10-14 years of age that previously received four doses of acellular pertussis vaccine. Group C: Adolescents 10-14 years of age who previously received four doses of whole-cell pertussis vaccine and have not yet received acellular pertussis vaccine and that simultaneously participate in the TRI05 study where they receive either REPEVAX® or COVAXiS® + IPV Merieux® depending on their randomization group.

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