Randomized, double-blind study for the evaluation of the effect of losartan versus placebo on aortic root dilatation in patients with Marfan syndrome under treatment with beta-blockers.

Registry ID

EUCTR2007-005862-10

Source registry

EUCTR

Status

Completed

Phase

PHASE3

Sponsor

University Hospital Ghent

Start date

2009-05-29

Last update

2026-08-16

Conditions

• Marfan syndrome

Summary

To study the effect of losartan (an angiotensin receptor blocker -ARB) on aortic root growth in patients with Marfan syndrome, already treated with beta-blockers (BB).

Locations

• , , Belgium

Related clinical trials

• Asprosin as a molecular marker for Marfan syndrome

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