Direct renin inhibitor (aliskiren)and carotid plaques instability markers in hypertensive patients requiring carotid endoarterectomy

Registry ID

EUCTR2009-016902-17

Source registry

EUCTR

Status

Temporarily Halted

Phase

PHASE2

Sponsor

AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI

Start date

2012-05-18

Last update

2026-08-16

Conditions

• Essential hypertension.

Summary

To determine the effects of a direct renin inhibitor on instability markers of carotid plaques from endoarterectomy. Primary endpoint are semiquantitative variations of mRNA levels of metalloproteasis 1,2,9 and 12.

Locations

• , , Italy

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