Fractures and Bisphosphonates: do bisphosphonates affect fracture healing?

Registry ID
EUCTR2011-000988-28
Source registry
EUCTR
Status
Completed
Phase
PHASE4
Sponsor
University of Edinburgh
Start date
2011-08-16
Completion date
2015-11-03
Last update
2026-08-16

Conditions

Summary

The aim of the study is to determine if alendronic acid - the drug most commonly used in the UK as treatment of osteoporosis (thinning bones) - affects fracture healing. Participants will be randomised to receive either alendronic acid or a placebo (a tablet that contains no active drug). The main objective will be to look at the x-rays that are taken 4 weeks into the study and compare the number of healed fractures in each group (alendronic acid or placebo). We will also look at how long it takes a fracture to heal, using the x-rays taken at weeks 2, 4, 6 and 8. One person will analyse all the x-rays in the study. The x-rays will be anonymised so that the reviewer is unaware of individual details or the treatment that the participant received.

Locations

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