Randomized Polycythemia Vera Symptom Study comparing the effectiveness and patient assessed effects of Ruxolitinib with Hydroxyurea in a Phase 3 trial

Registry ID

EUCTR2012-002318-37

Source registry

EUCTR

Status

Completed

Phase

PHASE3

Sponsor

Incyte Corporation

Start date

2012-10-02

Completion date

2016-06-24

Last update

2026-08-16

Conditions

• Polycythemia Vera

Summary

To compare the efficacy of ruxolitinib and HU for reducing the cluster of symptoms defined by tiredness, itching, muscle aches, night sweats, and sweats while awake in subjects with PV.

Locations

• , , Belgium
• , , Italy
• , , UK
• , , Ireland
• , , Spain

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• A Study of Rusfertide in Japanese Adults With Polycythemia Vera
• Observational Study on the Use of Ropeginterferon Alfa-2b in Polycythemia Vera (ROPEG-PV)
• A ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes
• INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

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