Keloid (scar) treatment assesment

Registry ID
EUCTR2012-002675-34
Source registry
EUCTR
Status
Ongoing
Phase
PHASE4
Start date
2012-06-29
Last update
2026-08-16

Conditions

Summary

Keloid disease is a tumorous scar that grows outside of wound borders. It appears as a raised, discoloured lesion that gives rise to aesthetic and psychosocial complaints, itching, and pain. Adequate treatment is indicated, but because of variable results and recurrence of the keloid current therapies are suboptimal. The Objective of the study is to find an effective and permanent treatment against keloid, by comparing current treatments on objective and subjective outcome. We will do this by a randomized controlled intervention study consistent of 2 parts, in oreder to remain close to clinical practice; 1) for primary keloids comparing intralesional cryotherapy with excision combined with corticosteroid injections 2) for recurrent keloids comparing intralesional cryotherapy with excision combined with brachytherapy This results in a total of 4 study arms; 2 in both parts of the study. Primary endpoint is Patient Observer Scar Assesment Scale (POSAS) score.

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