Safety and Efficacy of Brimonidine Posterior Segment Drug Delivery System in Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration (BEACON Study)

Registry ID
EUCTR2013-003320-36
Source registry
EUCTR
Status
Completed
Phase
PHASE2
Sponsor
Allergan Limited
Start date
2014-09-23
Completion date
2018-03-30
Last update
2026-08-16

Conditions

Summary

The study objectives are to assess: (1) the safety of the treatment; (2) the effects of treatment on the mean change in atrophic lesion area quantified from fundus autofluorescence images; (3) the effects of treatment on the mean change in low luminance best corrected visual acuity (BCVA); (4) the effects of treatment on the mean change in standard BCVA; (5) the effects of treatment on the mean change in retinal sensitivity quatified using scotopic/mesopic microperimetry; (6) to characterize the systemic pharmacokinetic profile of Brimo DDS.

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