A study to assess the new malaria vaccine RH5.1/AS01

Registry ID

EUCTR2016-001718-31

Source registry

EUCTR

Status

Completed

Phase

PHASE2

Sponsor

University of Oxford, CTRG

Start date

2016-08-24

Completion date

2019-06-27

Last update

2026-08-16

Conditions

• Plasmodium falciparum malaria

Summary

To assess the safety of the RH5.1/AS01 vaccine in healthy volunteers at different doses. To establish whether the RH5.1/AS01 vaccine can demonstrate a reduced parasite multiplication rate in vaccinated subjects compared to infectivity controls in a blood-stage controlled human malaria infection model.

Locations

• , , UK

Related clinical trials

• MAL RISK II: Risk of complications in outpatient treatment of imported Plasmodium falciparum malaria – an observational study in TropNet
• Determinants of semi-immunity and disease tolerance in malaria

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