PROTECTING FRONTLINE HEALTH CARE WORKERS FROM COVID-19 WITH HYDROXYCHLOROQUINE PRE-EXPOSURE PROPHYLAXIS: A RANDOMIZED, PLACEBO CONTROLLED MULTI SITE TRIAL IN TORONTO, CANADA

Registry ID

HEROS-1

Source registry

HEALTH_CANADA

Status

Ongoing

Study type

INTERVENTIONAL

Sponsor

UNIVERSITY HEALTH NETWORK

Start date

2020-04-29

Last update

2020-04-03

Conditions

• CORONAVIRUS DISEASE (COVID-19)

Related clinical trials

• ADAPTIVE PLATFORM TRIAL OF TREATMENTS FOR RESPIRATORY INFECTIONS IN COMMUNITY SETTINGS (TREATRESP)
• AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 3, DOUBLE-BLIND, 2-ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED IBUZATRELVIR COMPARED WITH PLACEBO IN NON-HOSPITALIZED SYMPTOMATIC ADULT AND ADOLESCENT PARTICIPANTS WITH COVID-19 WHO ARE AT HIGH RISK OF PROGRESSING TO SEVERE ILLNESS
• PHASE 1/2 STUDY TO EVALUATE SAFETY AND IMMUNOGENICITY OF A PROPHYLACTIC PLASMID DNA BOOSTER VACCINE AGAINST SARS-COV- -002] IN GENERALLY HEALTHY ADULTS 18 YEARS AND OLDER
• A PHASE 2 TRIAL TO EVALUATE SAFETY AND IMMUNOGENICITY OF A NEXT-GENERATION COVID-19 VACCINE DELIVERED BY INHALED AEROSOL TO HUMANS
• A PHASE I/III RANDOMIZED, DOUBLE-BLIND STUDY TO EVALUATE THE SAFETY AND NEUTRALIZING ACTIVITY OF AZD5156/AZD3152 FOR PRE-EXPOSURE PROPHYLAXIS OF COVID-19 IN PARTICIPANTS WITH CONDITIONS CAUSING IMMUNE IMPAIRMENT
• PLATFORM OF RANDOMIZED ADAPTIVE CLINICAL TRIALS IN CRITICAL ILLNESS (PRACTICAL) RANDOMIZED CONTROL TRIAL

View on source registry