Improving fetal growth restriction detection

An AI-driven fetal monitoring model to predict fetal growth restriction infants

Registry ID
ISRCTN10900816
Source registry
ISRCTN
Status
No longer recruiting
Study type
OBSERVATIONAL
Sponsor
University of Malaya
Enrollment
300
Start date
2023-02-01
Completion date
2025-06-30
Last update
2026-08-17

Conditions

Summary

Fetal growth restriction, small-for-gestational-age

Detailed description

In this research, the participants will undergo routine prenatal ultrasound scans throughout the entire pregnancy. This involves approximately five scans in total, which are conducted during the first, second and third trimesters. Besides that, the participants will have a non-invasive blood test during the first ultrasound scan, where 5 ml of blood will collect one time only. Every scan measures the fetus's growth to identify the growth-restricted fetuses earlier and take action to improve the outcomes for the growth-restricted fetus. The total duration of observation is typically from Week 11-14 until Week 36, which is around 6 months. The frequency of scans varies depending on the fetus’s condition, with some participants requiring weekly or bi-weekly scans.

Interventions

Inclusion criteria

Inclusion criteria for Phases 1, 2 and 3: 1. Pregnant women with age of between 21 and 50 years 2. Subjects are already scheduled for routine antenatal ultrasound evaluation

Exclusion criteria

Phases 1 and 2: 1. Fetuses with chromosomal and cardiovascular abnormalities and cases with incomplete data Phase 3: 1. Patients who, for any reason, are deemed unfit for blood taking, as determined by their physician 2. Fetus with chromosomal and cardiovascular abnormalities

Locations

Related clinical trials

View on source registry