Sleep apnoea symptoms and prevalence in people attending memory services
Sleep apnoea in patients attending memory clinics
Main study Participants will be asked to complete questionnaires to identify risk factors and symptoms relating to sleep apnoea and undergo a night of sleep apnoea screening using the WatchPAT polygraphy device. Data will also be collected from medical records. Participants will be informed of their results. Bloods sub-study Participants with sleep apnoea who are referred to treatment at the North Bristol site will be invited to undergo blood tests before and after treatment to assess whether blood biomarkers change following treatment for sleep apnoea. The study will also pilot a methodology for determining the change in serum biomarkers of Alzheimer’s disease and neurodegeneration after starting sleep apnoea treatment and report the change over time in biomarkers.
1. Patient attending an NHS memory clinic at an included recruitment site 2. Adults aged 18 or over 3. Patients who are able to consent for themselves Bloods sub-study only 1. New diagnosis of sleep apnoea 2. Recruited at the Bristol recruitment site 3. Referred to the sleep clinic 4. Consented to optional bloods sub-study when joining the study
1. Adults without capacity to consent to the research study. 2. Being unwilling to use the WatchPAT device. Bloods sub-study only 1. Being unwilling or unable to travel to the Bristol Brain Centre for blood tests, where blood tests at home are not feasible.