Intelligent platform for brain tumor diagnosis, treatment and recurrence monitoring

Comprehensive end-to-end intelligent platform for brain tumor diagnosis, treatment and recurrence monitoring using multimodal datasets

Registry ID
ISRCTN14076099
Source registry
ISRCTN
Status
Recruiting
Study type
OBSERVATIONAL
Sponsor
University of Malaya
Enrollment
500
Start date
2026-04-01
Completion date
2028-12-31
Last update
2026-08-17

Conditions

Summary

Brain tumour

Detailed description

This study employs a multimodal artificial intelligence (AI) approach integrating radiological and pathological imaging data for brain tumour diagnosis and treatment support. MRI scans will be collected and anonymised for data cleaning, preprocessing, and expert annotation. Other data collected include Whole Slide Image (WSI) reports, Isocitrate Dehydrogenase (IDH) reports, and clinical, demographic, radiological, pathological, and treatment-related data available in the medical records of patients diagnosed with brain tumours. All data will be anonymised before analysis. Deep learning models will be trained using public datasets for pre-operative tumour diagnosis and postoperative recurrence prediction and validated using local clinical datasets from PPUM. Segmentation models will also be developed for tumour and blood vessel identification and integrated with a surgical navigation platform to enhance precision and safety. The outcome will be an end-to-end intelligent platform for multimodal analysis, recurrence warning, and surgical planning assistance.

Interventions

Inclusion criteria

1. Patients diagnosed with primary brain tumour 2. Patients who underwent standard of care procedure at University of Malaya Medical Centre (UMMC)

Exclusion criteria

1. Patients diagnosed with other types of brain disease

Locations

Related clinical trials

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