LymphSEARCH screening study - Incidence and prognostic factors for secondary lymphoedema in breast cancer patients
Lymphoedema in breast cancer patients
Observational: Patients are included after breast cancer diagnosis but before start of treatment. A baseline visit is performed with assessment of arm volume, bioimpedance, biomarkers, genetics, patient-reported outcome measures and mapping of lymphatic vessel anatomy in addition to clinical background data. Observation period is 2 years with subsequent visits for repeated measures at 3, 6, 12, 24, 36 months which is also end of follow-up.
1. Females age 18 years or older 2. Diagnosis of invasive breast cancer 3. Planned breast cancer treatment at Uppsala University Hospital 4. Informed written consent to participate in the study
1. Guardians or subjects who, in the opinion of the Investigator, may be non-compliant with study schedules or procedures. 2. Previous diagnosis of lymphoedema in the upper extremity 3. Previous bilateral radiotherapy treatment for diagnosis other than breast cancer (ipsilateral radiotherapy is not an exclusion criterion, i.e. same side as current breast cancer diagnosis) 4. Previous chemotherapy for a malignant diagnosis other than breast cancer within 12 months prior to breast cancer diagnosis 5. Previous axillary surgery for diagnosis other than breast cancer