Preventing long-term conditions in people with high blood pressure through lifestyle changes

Healthier You Hypertension pilot to prevent long-term conditions

Registry ID
ISRCTN15193947
Source registry
ISRCTN
Status
Recruiting
Study type
INTERVENTIONAL
Sponsor
Chelsea and Westminster Hospital NHS Foundation Trust
Enrollment
130000
Start date
2026-01-01
Completion date
2028-12-31
Last update
2026-08-17

Conditions

Summary

Hypertension and subsequent development of other long-term conditions

Detailed description

A stepped-wedge cluster randomised controlled trial in 216 GP practices (clusters) within eight Integrated Care Systems (ICSs) in England over 4 years. In year one, all GP practices will offer usual care.  In year two, a third of GP practices will be randomly allocated to start to offer interventions while the remaining two-thirds will continue to offer usual care. In year three, a further third of GP practices will be randomly allocated to start to offer the interventions while the remaining third will continue to offer usual care. In year four, the final third of GP practices will start offering the interventions, so that interventions will then be offered by all 216 GP practices. All individuals living with hypertension within the intervention clusters will be eligible to be referred to the Healthier You Hypertension Pilot to Prevent Long-Term Conditions, a 9-month lifestyle intervention supporting weight loss, increased physical activity and better quality nutrition with a choice of face-to-face or digital delivery. Face-to-face delivery consists of 13 group-based intervention sessions over the 9-month period, while digital delivery is delivered at the individual level and consists of 9 engagement periods (including a digital registration), each lasting 30 days. All individuals within the control clusters will receive usual care.

Interventions

Inclusion criteria

1. Diagnosed with hypertension and aged 18 years or over. 2. Individuals who are aged 80 years and older are eligible to access the programme if their clinician referrer provides written confirmation that the referrer perceives the benefits of the study outweigh any potential risks of participating in a weight loss programme for that individual.

Exclusion criteria

1. Individuals with diabetes or non-diabetic hyperglycaemia 2. Individuals with an eating disorder 3. Individuals with severe/moderate frailty 4. Individuals who have undergone bariatric surgery in the last 2 years 5. Individuals aged under 18 years 6. Pregnant women

Locations

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