Suicidality in children and adolescents, neurobiological parameters, and their mutual association.
Incidence of suicide attempts in the last seven days, Incidence of suicidal ideations.
The research group will consist of 60 patients who will be divided into two groups: patients with suicidal ideations (SI) and patients after suicide attempts (SA). The enrolled patients will be asked to fill out the following scales: the self-report Symptom Checklist 90 (SCL90R), the Child Depression Inventory (CDI) self-report questionnaire, and the self-report Yale Vermont Adversity in Childhood Scale (Y-VACS-SR) The examiner will investigate depressive symptoms severity using the Children's Depression Rating Scale-Revised (CDRS-R) and suicide risk using the Columbia Suicide Severity Rating Scale (C-SSRS). Biological material (blood, urine, hair) of patients and healthy controls will be collected, processed using standard clinical biochemistry methods, and stored at -80° C.
1. Patients hospitalized at the Department of Paediatric Psychiatry of the Comenius University, Medical Faculty and the National Institute of Children's Diseases, age 10-17 years. 2. Signed informed consent by the legal guardian. 3. Verbal consent of the patient to be included in the project. 4. Presence of suicidal ideation and/or suicide attempts. 5. Children and adolescents are willing to provide blood, urine, and hair samples.
Chronic somatic inflammatory and oncological disease