Perioperative complications and autonomic function assessed by the COMPASS-31 tool

Perioperative complications and autonomic function assessed by the COMPASS-31 tool: multicentre, observational, mechanistic cohort study

Registry ID

ISRCTN17277871

Source registry

ISRCTN

Status

Recruiting

Study type

OBSERVATIONAL

Sponsor

Queen Mary University of London

Enrollment

296

Start date

2025-11-15

Completion date

2027-11-15

Last update

2026-08-17

Conditions

• Nervous System Diseases

Summary

Autonomic function in people undergoing major noncardiac surgery under general anaesthesia

Detailed description

Composite Autonomic Symptom Score-31 within 30 days after surgery.

Interventions

• OTHER: Composite Autonomic Symptom Score-31 within 30 days after surgery.

Inclusion criteria

1. Patients aged ≥ 50 years and over undergoing elective major noncardiac surgery under general anaesthesia expected to require at least an overnight stay in hospital.

Exclusion criteria

1. Lack of capacity or refusal to provide written informed consent 2. Inability to complete questionnaires 2. American Society of Anesthesiologists (ASA) score of I

Locations

• , , United Kingdom
• , , England

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