Can vitamin supplements help school children in healing gum diseases?

Effectiveness of Vitamin C and Vitamin D supplements in the treatment of periodontal diseases in school-going children

Registry ID
ISRCTN18356310
Source registry
ISRCTN
Status
No longer recruiting
Study type
INTERVENTIONAL
Sponsor
University of Lahore
Enrollment
306
Start date
2021-10-01
Completion date
2024-02-05
Last update
2026-08-17

Conditions

Summary

Periodontal disease

Detailed description

Cross-sectional phase 1 for baseline assessment followed by interventional phase 2 with modified RCT protocol among two groups (Group A with non-deficient children and group B with deficient children) to allow for intervention to only be given to children who were deficient, blinding done by switching of examiners between baseline assessment, intervention and follow-up examination. First visit (baseline): each child (and a parent) answers a short questionnaire about home dental habits, demographics, and vitamin deficiency and then has a dental checkup. Group allocation: Group A (control): professional ultrasonic scaling + dental hygiene advice. Group B (vitamin C and D deficient group): the same scaling and advice plus vitamin C and D supplements. Follow-up visits: after 4 weeks and again after 8 weeks the dentists re-measure the Gingival Index and pocket depth. All children receive the same brushing advice at every visit.

Interventions

Inclusion criteria

1. School-going children 2. No systemic diseases 3. Not taking antibiotic therapy 4. 4-12 years of age

Exclusion criteria

1. Participants with systemic disease like diabetes or otherwise immunocompromised 2. Participants taking antibiotics

Locations

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