A multicenter, prospective, randomized controlled trial of surgical versus conservative treatment in patients with temporomandibular joint anterior displacement without reduction
Anterior disc displacement of the temporomandibular joint without reduction
Current interventions as of 11/03/2024: This study is a multicenter, prospective, randomized controlled trial assessing the efficacy of surgical versus conservative treatments in adult temporomandibular joint anterior disc displacement without reduction (TMJ ADDWoR), investigating the effects of surgical and conservative treatments on TMJ function and psychological state in adults with ADDWoR. The study aims to develop a clinical diagnosis and treatment system for ADDWoR by collecting a total of 90 patients from multicenter, controlled trials. Patients are divided into two groups for treatment: conservative and surgical, with follow-ups at 1 , 6, 12, and 24 months. Randomization: The researchers employed a robust and transparent method using specialized software designed for clinical trials to randomize participants in their study. After enrolling participants, they input the total participant count into this software, which then randomly allocated them into two distinct groups: one for surgical treatment and another for conservative treatment. This randomization was primarily achieved using a simple yet effective method based on odd and even numbers, which ensured an unbiased and equitable distribution of participants across both treatment arms. The integrity of the randomization process was meticulously documented and monitored throughout the trial to maintain consistency and fairness. Blinding: As for blinding, the researchers acknowledge the limitations of their study in this regard. Due to the inherently visible and distinct differences between the surgical and conservative treatment modalities, blinding was not feasible. The participants and the clinicians were unavoidably aware of the treatment being administered. This awareness stems from the physical and procedural distinctions between the two types of interventions, making any form of blinding impossible to implement. The researchers recognize that this aspect could introduce certain biases and have acco
1. Patients with temporomandibular joint anterior disc displacement without reduction (ADDWoR) who have not previously been treated 2. Available and well-preserved clinical data 3. Adults aged 18 to 55 years old
1. Presence of biased chewing habits or significant occlusal interference 2. Presence of other severe illnesses or organ dysfunction 3. Incomplete clinical data 4. Individuals under the age of 18 years