Host Response to Infection and Treatment in Lymphatic Filarial Disease in India Patients admitted on this protocol will have, or be suspected of having, one of the lymphatic filarial infections affecting humans. After routine clinical evaluation they will be studied i...

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Immune Responses to Mycobacterium Tuberculosis (Mtb) in People With Latent Tuberculosis Infection With or Without Concomitant Helminth Infection Background: Tuberculosis (TB) is a severe disease and a major cause of death in many people worldwide. It is caused by a bacteria that enters through the lungs and can spread elsewhere in...

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Effect of Albendazole Dose on Treatment of Lymphatic Filariasis This study is conducted in Kerala, India. It will determine whether a new treatment regimen of albendazole and diethylcarbamazine (DEC) for lymphatic filariasis can eliminate the disease m...

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Effect of Filarial Infection on Immune Responses in Latent Tuberculosis Background: - Lymphatic filariasis is an infection that is caused by small, thread-like worms. It is spread by mosquitoes, and causes fever, chills, and headaches. If untreated, it can al...

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Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection The purpose of this study is to evaluate, treat and follow patients with parasitic infections. People with a known or suspected parasitic infection who are at least 1 year old may be ...

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Comparison of Immune Response in Normal Volunteers and Patients With Helminth Infections This study will compare the structure, chemical composition and other characteristics of skin and blood in people with and without parasitic infections. Cell samples will be taken from bli...

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Apheresis to Obtain Plasma or White Blood Cells for Laboratory Studies This study will collect blood plasma and white blood cells for laboratory research using a procedure called apheresis. Apheresis is a method of collecting larger quantities of certain bloo...

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Host Response to Infection and Treatment in Filarial Diseases This study will evaluate and treat patients with filarial infections to explore in depth the immunology of the disease, including susceptibility to infection, disease development, and resp...

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