Extrait

To compare histamine release and its effects on cardiac dysrhythmias in the peri-operative period in adult patients undergoing cardiac operations involving cardiopulmonary bypass with and without H1- and H2-receptor antagonist prophylaxis.

Critère d'inclusion

• During cardiac surgery involving the use of cardiopulmonary bypass histamine is released in the blood. Histamine release has been related to an increased incidence of perioperative dysrhythmias and may be involved in other complications. Our aim is to find out whether the use of histamine blocking drugs will prevent these arrhythmias. The study population will consist of adult patients who must undergo elective cardiac surgery in which the use of cardiopulmonary bypass is necessary

Liens

• euctr
• ictrp
• ictrp
• isrctn