Woman and Man
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Extract
To establish effectiveness on severity of depression (measured by PHQ-9), of a closely monitored integrated intervention (TCCCL + duloxetine) for concomitant (sub)chronic pain and depression compared to TCCCL + placebo and compared to Duloxetine alone.
Inclusion criteria
- Major depressive disorder (episode or recurrent), as principal DSM-IV diagnosis combined with (sub)chronic pain symptoms as defined bij score of >3 on BPI painlist for at least six weeks