Extrait

To establish a model of dose-dependent bronchodilation that will be used to establish the pharmacodynamic equivalency of the LABA component of new combination asthma drug treatments. The intention to better characterize the timecourse of bronchodilatory changes following a single treatment with 3 doses of Advair® 100 / 50 (1 puff, 2 puffs or 4 puffs; equivalent to 100/50, 200/100 and 400/200 mcg, fluticasone/salmeterol respectively).

Critère d'inclusion

• Asthma

Liens

• ictrp
• euctr