Extrait

i. For patients who are considered fit for an intensive chemotherapy approach to treatment. ii. For patients who are not considered fit for an intensive approach to treatment. The objectives for each of these components are summarised below. 2.1 Therapeutic questions for patients considered fit for intensive treatment: — To compare two induction schedules (DA and DClo). — To assess the value of Mylotarg during induction when used in combination with DA or DClo in course 1. — — To compare two versus three courses of induction/consolidation treatment in patients who achieve at least a Partial Response to induction course 1. — To compare the use of Demethylation maintenance treatment with Azacitidine with no maintenance — To assess the value of Reduced Intensity Allogeneic Stem Cell Transplantation as consolidation for patients with matched donors.

Critère d'inclusion

• Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome

Liens

• ictrp
• euctr
• euctr