A pilot study to assess the effect of regulatory T-cell depletion on 5T4-containing MVA(TroVax®)vaccination in patients with inoperable metastatic colorectal cancer

Mise à jour : Il y a 4 ans
Référence : EUCTR2010-024380-41

Femme et Homme

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Extrait

The main objective is to investigate whether an immune cell population that acts against the clinical benefit of the patient (i.e. in favour of the development of cancer) can be specifically reduced. This would lead to enhanced anti-tumour immune responses observed, as it has already been observed in rodents. The research question will be asked in patients with inoperable metastatic colorectal cancer.


Critère d'inclusion

  • Inoperable metastatic colorectal cancer