Do sulphponylureas preserve cortical function during hypoglycaemia in patients with type 1 diabetes and hypoglycaemia unawareness?

Mise à jour : Il y a 4 ans
Référence : EUCTR2007-000497-23

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Extrait

To evaulate the effect of K ATP channel blockade with glibenclamide on the symptomatic and counterregulatory hormonal responses to experimental hypoglycaemia.


Critère d'inclusion

  • We are testing the hypothesis that closing the K ATP channels using sulphonylureas (glibenclamide) during experimental insulin induced hypoglycaemia can help retain cerebral function and help enhance symptoms of hypoglycaemia in those with type 1 diabetes and hypoglycaemia unawareness

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