Prospective, randomized study of the efficacy of photodynamic therapy in actinic keratosis

Mise à jour : Il y a 4 ans
Référence : EUCTR2008-000459-88

Femme et Homme

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Extrait

Our preliminary experience with the Hydrosun-radiator (halogen lamp) indicates that photodynamic therapy (PDT) with visible light (VIS) and water-filtered infrared A (wIRA) compared to conventional light sources such as Aktilite 128 (light-emitting diode, LED) is significantly less painful. We therefore want to investigate on the one hand the influence of wIRA on pain sensations during PDT and to document the treatment success. On the other hand, we want to investigate the influence of wIRA on the penetration depth and thereby on therapeutic outcome. The questions are therefore: I. Is there less pain during VIS/wIRA-PDT compared to VIS-PDT? II Is the therapeutic effect of the VIS/wIRA-PDT worse, comparable to or better than those of the VIS-PDT? III. Can the therapeutic efficacy of PDT be improved by promoting the penetration of the photosensitizer?


Critère d'inclusion

  • We treat patients with superficial actinic keratosis grade I-II on the face or scalp

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