A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE PREVENTION AND TREATMENT OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY SYMPTOMS WITH PREGABALIN IN SUBJECTS WITH ADVANCED COLORECTAL CANCER

Update Il y a 4 ans
Reference: EUCTR2006-002917-11

Woman and Man

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Extract

• To evaluate the time to onset of moderate-severe persistent paresthesic positive symptoms of chemotherapy-induced neuropathy defined as a minimum score ≥ 4 assessed with the Numeric Rating Scale (NRS) from the onset of chemotherapy or emergence of a chemotherapy dose reduction or delay of chemotherapy cycle due to severity of chemotherapy-induced neuropathy. The persistent paresthesic positive symptoms will be measured by a modified NRS (Numeric Rating Scale) which assesses paresthesia rather than pain.


Inclusion criteria

  • CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY SYMPTOMS